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HomoloGene:1389. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CNR2,  H.sapiens
cannabinoid receptor 2 (macrophage)
NP_001832.1
360 aa
CNR2,  P.troglodytes
cannabinoid receptor 2 (macrophage)
XP_513201.1
360 aa
CNR2,  M.mulatta
cannabinoid receptor 2 (macrophage)
XP_001105018.1
360 aa
CNR2,  C.lupus
cannabinoid receptor 2 (macrophage)
XP_005617868.1
360 aa
CNR2,  B.taurus
cannabinoid receptor 2 (macrophage)
NP_001179232.1
361 aa
Cnr2,  M.musculus
cannabinoid receptor 2 (macrophage)
NP_034054.3
347 aa
Cnr2,  R.norvegicus
cannabinoid receptor 2 (macrophage)
NP_001157614.1
360 aa
CNR2,  G.gallus
cannabinoid receptor 2 (macrophage)
XP_004947955.1
351 aa
cnr2,  X.tropicalis
cannabinoid receptor 2 (macrophage)
XP_002938788.1
357 aa
cnr2,  D.rerio
cannabinoid receptor 2
NP_998129.3
383 aa
LOC101885436,  D.rerio
cannabinoid receptor 2-like
XP_005156430.1
317 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Cannabinoid receptor CB2 modulates axon guidance.
Duff G, et al. PLoS One 8, e70849 (2013).
Cannabinoid receptor 2 protects against acute experimental sepsis in mice.
Gui H, et al. Mediators Inflamm 2013, 741303 (2013).
Identification of raloxifene as a novel CB2 inverse agonist.
Kumar P & Song ZH. Biochem Biophys Res Commun 435, 76-81 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cnr2 includes H.sapiens CNR2 and R.norvegicus Cnr2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 9 species)
Actinopterygii - bony fishes (1 transcript, 1 species)

 

 

 

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