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HomoloGene:2373. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

STAT6,  H.sapiens
signal transducer and activator of transcription 6, interleukin-4 induced
NP_001171550.1
847 aa
STAT6,  P.troglodytes
signal transducer and activator of transcription 6, interleukin-4 induced
XP_003952193.1
858 aa
STAT6,  M.mulatta
signal transducer and activator of transcription 6, interleukin-4 induced
XP_002798683.1
847 aa
STAT6,  C.lupus
signal transducer and activator of transcription 6, interleukin-4 induced
XP_003431490.1
844 aa
STAT6,  B.taurus
signal transducer and activator of transcription 6, interleukin-4 induced
NP_001192430.1
847 aa
Stat6,  M.musculus
signal transducer and activator of transcription 6
NP_033310.2
837 aa
Stat6,  R.norvegicus
signal transducer and activator of transcription 6, interleukin-4 induced
NP_001037715.1
841 aa
stat6,  X.tropicalis
signal transducer and activator of transcription 6, interleukin-4 induced
XP_002939755.1
787 aa
stat6,  D.rerio
signal transducer and activator of transcription 6, interleukin-4 induced
NP_001124062.1
758 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

STAT6 - polymorphisms, haplotypes and epistasis in relation to atopy and asthma.
Godava M, et al. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 157, 172-80 (2013).
Polymorphisms of STAT6 and specific serum IgE levels in patients with penicillin allergy.
Huang CZ, et al. Int J Clin Pharmacol Ther 50, 461-7 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
STAT_bind (pfam02864)
  STAT protein, DNA binding domain.
STAT_alpha (pfam01017)
  STAT protein, all-alpha domain.
STAT_int (pfam02865)
  STAT protein, protein interaction domain.
STAT_alpha (pfam01017)
  STAT protein, all-alpha domain.
STAT6_C (pfam14596)
  STAT6 C-terminal.
STAT_int (cl03749)
  STAT protein, protein interaction domain.
SH2 (cl15255)
  Src homology 2 (SH2) domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Stat6 includes H.sapiens STAT6 and R.norvegicus Stat6.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 13 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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