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HomoloGene:15433. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

NEU4,  H.sapiens
sialidase 4
NP_001161071.1
497 aa
NEU4,  M.mulatta
sialidase 4
XP_001095081.2
497 aa
NEU4,  B.taurus
sialidase 4
XP_002686672.1
478 aa
Neu4,  M.musculus
sialidase 4
NP_776133.1
478 aa
Neu4,  R.norvegicus
sialidase 4
NP_001101704.1
478 aa
NEU4,  G.gallus
sialidase 4
XP_004937059.1
473 aa
LOC100486976,  X.tropicalis
sialidase-4-like
XP_002943103.2
482 aa
neu4,  D.rerio
sialidase 4
NP_001018384.1
429 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Identification and expression of Neu4, a novel murine sialidase.
Comelli EM, et al. Gene 321, 155-61 (2003).
Human sialidase as a cancer marker.
Miyagi T, et al. Proteomics 8, 3303-11 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Sialidase (cd00260)
  Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Neu4 includes H.sapiens NEU4 and R.norvegicus Neu4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (5 transcripts, 5 species)
Actinopterygii - bony fishes (1 transcript, 1 species)

 

 

 

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