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HomoloGene:32415. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PBK,  H.sapiens
PDZ binding kinase
NP_060962.2
322 aa
PBK,  P.troglodytes
PDZ binding kinase
NP_001233441.1
322 aa
PBK,  M.mulatta
PDZ binding kinase
XP_001109768.1
323 aa
PBK,  C.lupus
PDZ binding kinase
XP_534564.1
324 aa
PBK,  B.taurus
PDZ binding kinase
NP_001095648.1
324 aa
Pbk,  M.musculus
PDZ binding kinase
NP_075698.1
330 aa
Pbk,  R.norvegicus
PDZ binding kinase
NP_001073406.1
337 aa
PBK,  G.gallus
PDZ binding kinase
NP_001264928.1
322 aa
pbk,  X.tropicalis
PDZ binding kinase
NP_001011346.1
325 aa
pbk,  D.rerio
PDZ binding kinase
NP_001002387.1
339 aa
CG8173,  D.melanogaster
CG8173
NP_573239.1
398 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Expression and phosphorylation of TOPK during spermatogenesis.
Fujibuchi T, et al. Dev Growth Differ 47, 637-44 (2005).
PDZ-binding kinase participates in spermatogenesis.
Zhao S, et al. Int J Biochem Cell Biol 33, 631-6 (2001).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Pkinase (pfam00069)
  Protein kinase domain.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pbk includes H.sapiens PBK and R.norvegicus Pbk.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (8 transcripts, 8 species)
Amphibia - amphibians (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 7 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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