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HomoloGene:8359. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ANAPC2,  H.sapiens
anaphase promoting complex subunit 2
NP_037498.1
822 aa
ANAPC2,  P.troglodytes
anaphase promoting complex subunit 2
XP_520643.3
811 aa
ANAPC2,  M.mulatta
anaphase promoting complex subunit 2
XP_001090195.1
822 aa
ANAPC2,  C.lupus
anaphase promoting complex subunit 2
XP_548357.2
818 aa
Anapc2,  M.musculus
anaphase promoting complex subunit 2
NP_780509.2
837 aa
Anapc2,  R.norvegicus
anaphase promoting complex subunit 2
NP_001094002.1
836 aa
ANAPC2,  G.gallus
anaphase promoting complex subunit 2
XP_415533.2
810 aa
anapc2,  X.tropicalis
anaphase promoting complex subunit 2
XP_004917614.1
564 aa
anapc2,  D.rerio
anaphase promoting complex subunit 2
NP_001243675.1
802 aa
mr,  D.melanogaster
morula
NP_611862.1
802 aa
AgaP_AGAP005048,  A.gambiae
AgaP_AGAP005048
XP_313920.4
783 aa
APC2,  A.thaliana
APC2
NP_178543.2
865 aa
Os04g0484800,  O.sativa
Os04g0484800
NP_001053127.2
864 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Human APC2 localization and allelic imbalance.
Jarrett CR, et al. Cancer Res 61, 7978-84 (2001).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
APC2 (pfam08672)
  Anaphase promoting complex (APC) subunit 2.
Cullin (pfam00888)
  Cullin family.
Cullin (pfam00888)
  Cullin family.
APC2 (cl08488)
  The anaphase promoting complex or cyclosome (APC2) is an E3 ubiquitin ligase which is part of the SCF family of ubiquitin ligases. Ubiquitin ligases catalyse the transfer of ubiquitin from the ubiquitin conjugating enzyme (E2), to the substrate protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Anapc2 includes H.sapiens ANAPC2 and R.norvegicus Anapc2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (9 transcripts, 8 species)
Arachnida - arachnids (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (14 transcripts, 12 species)
Liliopsida - monocots (8 transcripts, 5 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

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