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HomoloGene:3964. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

XRCC2,  H.sapiens
X-ray repair complementing defective repair in Chinese hamster cells 2
NP_005422.1
280 aa
XRCC2,  P.troglodytes
X-ray repair complementing defective repair in Chinese hamster cells 2
XP_001140134.1
280 aa
XRCC2,  M.mulatta
X-ray repair complementing defective repair in Chinese hamster cells 2
XP_001108141.1
280 aa
XRCC2,  C.lupus
X-ray repair complementing defective repair in Chinese hamster cells 2
XP_532771.3
279 aa
XRCC2,  B.taurus
X-ray repair complementing defective repair in Chinese hamster cells 2
NP_001095824.1
280 aa
Xrcc2,  M.musculus
X-ray repair complementing defective repair in Chinese hamster cells 2
NP_065595.2
278 aa
Xrcc2,  R.norvegicus
X-ray repair complementing defective repair in Chinese hamster cells 2
NP_001102685.1
278 aa
XRCC2,  G.gallus
X-ray repair complementing defective repair in Chinese hamster cells 2
XP_418543.3
278 aa
xrcc2,  X.tropicalis
X-ray repair complementing defective repair in Chinese hamster cells 2
XP_002932541.2
282 aa
LOC553395,  D.rerio
uncharacterized LOC553395
XP_685091.2
302 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Rare variants in XRCC2 as breast cancer susceptibility alleles.
Hilbers FS, et al. J Med Genet 49, 618-20 (2012).
Rare mutations in XRCC2 increase the risk of breast cancer.
Park DJ, et al. Am J Hum Genet 90, 734-9 (2012).
Genetic variants in XRCC2: new insights into colorectal cancer tumorigenesis.
Curtin K, et al. Cancer Epidemiol Biomarkers Prev 18, 2476-84 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
P-loop_NTPase (cl09099)
  P-loop containing Nucleoside Triphosphate Hydrolases.
P-loop_NTPase (cl09099)
  P-loop containing Nucleoside Triphosphate Hydrolases.
RecA-like_NTPases (cl17233)
  RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and ...
RecA-like_NTPases (cl17233)
  RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Xrcc2 includes H.sapiens XRCC2 and R.norvegicus Xrcc2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 9 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

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