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HomoloGene:32615. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

DHDDS,  H.sapiens
dehydrodolichyl diphosphate synthase
NP_079163.2
334 aa
DHDDS,  P.troglodytes
dehydrodolichyl diphosphate synthase
XP_513233.2
334 aa
DHDDS,  M.mulatta
dehydrodolichyl diphosphate synthase
XP_001109408.1
334 aa
DHDDS,  C.lupus
dehydrodolichyl diphosphate synthase
XP_854980.2
333 aa
DHDDS,  B.taurus
dehydrodolichyl diphosphate synthase
NP_001030423.1
316 aa
Dhdds,  M.musculus
dehydrodolichyl diphosphate synthase
NP_080420.2
333 aa
Dhdds,  R.norvegicus
dehydrodolichyl diphosphate synthase
NP_001011978.1
333 aa
DHDDS,  G.gallus
dehydrodolichyl diphosphate synthase
XP_417694.2
333 aa
dhdds,  X.tropicalis
dehydrodolichyl diphosphate synthase
NP_001107380.1
332 aa
dhdds,  D.rerio
dehydrodolichyl diphosphate synthase
NP_998352.1
335 aa
CG10778,  D.melanogaster
CG10778
NP_572425.1
300 aa
AgaP_AGAP002026,  A.gambiae
AgaP_AGAP002026
XP_003436008.1
332 aa
AgaP_AGAP012908,  A.gambiae
AgaP_AGAP012908
XP_307411.2
181 aa
T01G1.4,  C.elegans
T01G1.4
NP_001023351.1
299 aa
RER2,  S.cerevisiae
RER2
NP_009556.1
286 aa
KLLA0E17205g,  K.lactis
KLLA0E17205g
XP_454725.1
275 aa
AGOS_AER003C,  E.gossypii
AGOS_AER003C
NP_984863.1
274 aa
SPAC4D7.04c,  S.pombe
SPAC4D7.04c
NP_594957.1
264 aa
MGG_12110,  M.oryzae
MGG_12110
XP_003719914.1
351 aa
NCU03460,  N.crassa
NCU03460
XP_956051.1
359 aa
AT2G17570,  A.thaliana
AT2G17570
NP_565420.1
295 aa
Os07g0607700,  O.sativa
Os07g0607700
NP_001060237.1
299 aa
Os06g0167400,  O.sativa
Os06g0167400
NP_001056920.1
299 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
???.



Publications
Articles associated with genes and sequences of this homology group.

Polyprenyl lipid synthesis in mammalian cells expressing human cis-prenyl transferase.
Jones J, et al. Biochem Biophys Res Commun 331, 379-83 (2005).
Identification of human dehydrodolichyl diphosphate synthase gene.
Endo S, et al. Biochim Biophys Acta 1625, 291-5 (2003).
Whole-exome sequencing links a variant in DHDDS to retinitis pigmentosa.
Züchner S, et al. Am J Hum Genet 88, 201-6 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Prenyltransf (pfam01255)
  Putative undecaprenyl diphosphate synthase.
CIS_IPPS (cd00475)
  Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl ...
Cis_IPPS (cl00230)
  Cis (Z)-Isoprenyl Diphosphate Synthases.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dhdds includes H.sapiens DHDDS and R.norvegicus Dhdds.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 12 species)
Actinopterygii - bony fishes (9 transcripts, 9 species)
Ascidiacea - tunicates (5 transcripts, 3 species)
Aves - birds (3 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 8 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (18 transcripts, 15 species)
Liliopsida - monocots (10 transcripts, 9 species)

Ascomycota
Sordariomycetes - ascomycetes (5 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

 

 

 

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