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HomoloGene:68209. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CRYAB,  H.sapiens
crystallin, alpha B
NP_001876.1
175 aa
CRYAB,  P.troglodytes
crystallin, alpha B
XP_508752.2
175 aa
CRYAB,  M.mulatta
crystallin, alpha B
XP_002799808.1
175 aa
CRYAB,  C.lupus
crystallin, alpha B
XP_862258.2
175 aa
CRYAB,  B.taurus
crystallin, alpha B
NP_776715.1
175 aa
Cryab,  M.musculus
crystallin, alpha B
NP_034094.1
175 aa
Cryab,  R.norvegicus
crystallin, alpha B
NP_037067.1
175 aa
CRYAB,  G.gallus
crystallin, alpha B
NP_990507.1
174 aa
cryab,  X.tropicalis
crystallin, alpha B
XP_002932964.1
173 aa
cryabb,  D.rerio
crystallin, alpha B, b
NP_001002670.1
165 aa
l(2)efl,  D.melanogaster
lethal (2) essential for life
NP_523827.1
187 aa
AgaP_AGAP007162,  A.gambiae
AgaP_AGAP007162
XP_308606.2
192 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Cataract, posterior polar 2.
Myopathy, cardioskeletal, desmin-related, with cataract.



Publications
Articles associated with genes and sequences of this homology group.

One size does not fit all: the oligomeric states of αB crystallin.
Delbecq SP & Klevit RE. FEBS Lett 587, 1073-80 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Crystallin (pfam00525)
  Alpha crystallin A chain, N terminal.
Crystallin (pfam00525)
  Alpha crystallin A chain, N terminal.
alpha-crystallin-Hsps_p23-like (cl00175)
  alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cryab includes H.sapiens CRYAB and R.norvegicus Cryab.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Arthropoda
Insecta - insects (51 transcripts, 12 species)
Arachnida - arachnids (3 transcripts, 2 species)

Chordata
Mammalia - mammals (23 transcripts, 17 species)
Actinopterygii - bony fishes (4 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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