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HomoloGene:1826. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

MPP1,  H.sapiens
membrane protein, palmitoylated 1, 55kDa
466 aa
MPP1,  P.troglodytes
membrane protein, palmitoylated 1, 55kDa
466 aa
MPP1,  M.mulatta
membrane protein, palmitoylated 1, 55kDa
466 aa
MPP1,  C.lupus
membrane protein, palmitoylated 1, 55kDa
466 aa
MPP1,  B.taurus
membrane protein, palmitoylated 1, 55kDa
466 aa
Mpp1,  M.musculus
membrane protein, palmitoylated
466 aa
MPP1,  G.gallus
membrane protein, palmitoylated 1, 55kDa
468 aa
mpp1,  X.tropicalis
membrane protein, palmitoylated 1, 55kDa
460 aa
mpp1,  D.rerio
membrane protein, palmitoylated 1
468 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

The role of MPP1/p55 and its palmitoylation in resting state raft organization in HEL cells.
Biernatowska A, et al. Biochim Biophys Acta 1833, 1876-84 (2013).
Solution structure of human erythroid p55 PDZ domain.
Kusunoki H & Kohno T. Proteins 64, 804-7 (2006).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Guanylate_kin (pfam00625)
  Guanylate kinase.
SH3 (cl17036)
  Src Homology 3 domain superfamily.
Guanylate_kin (pfam00625)
  Guanylate kinase.
PDZ (cl00117)
  PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...
SH3 (cl17036)
  Src Homology 3 domain superfamily.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mpp1 includes H.sapiens MPP1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (17 transcripts, 16 species)
Actinopterygii - bony fishes (14 transcripts, 11 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Coccidia - apicomplexans (1 transcript, 1 species)




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