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HomoloGene:2267. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SFRP4,  H.sapiens
secreted frizzled-related protein 4
NP_003005.2
346 aa
SFRP4,  P.troglodytes
secreted frizzled-related protein 4
XP_519048.3
368 aa
SFRP4,  M.mulatta
secreted frizzled-related protein 4
NP_001028134.1
346 aa
SFRP4,  C.lupus
secreted frizzled-related protein 4
XP_540377.2
347 aa
SFRP4,  B.taurus
secreted frizzled-related protein 4
NP_001069232.1
346 aa
Sfrp4,  M.musculus
secreted frizzled-related protein 4
NP_057896.1
351 aa
Sfrp4,  R.norvegicus
secreted frizzled-related protein 4
NP_445996.1
348 aa
SFRP4,  G.gallus
secreted frizzled-related protein 4
XP_418831.4
362 aa
sfrp4,  X.tropicalis
secreted frizzled-related protein 4
XP_002939467.2
353 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Expression and regulation of sFRP family members in human granulosa cells.
Maman E, et al. Mol Hum Reprod 17, 399-404 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CRD_FZ (cl02447)
  CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain.
NTR_like (cl02512)
  NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...
CRD_FZ (cl02447)
  CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain.
NTR_like (cl02512)
  NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Sfrp4 includes H.sapiens SFRP4 and R.norvegicus Sfrp4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)

 

 

 

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