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HomoloGene:65982. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

CSMD3,  H.sapiens
CUB and Sushi multiple domains 3
3707 aa
CSMD3,  P.troglodytes
CUB and Sushi multiple domains 3
3713 aa
CSMD3,  M.mulatta
CUB and Sushi multiple domains 3
3661 aa
CSMD3,  C.lupus
CUB and Sushi multiple domains 3
3707 aa
Csmd3,  M.musculus
CUB and Sushi multiple domains 3
3707 aa
Csmd3,  R.norvegicus
CUB and Sushi multiple domains 3
3517 aa
CSMD3,  G.gallus
CUB and Sushi multiple domains 3
3706 aa
LOC572419,  D.rerio
CUB and sushi domain-containing protein 3-like
3558 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Functionally enigmatic genes: a case study of the brain ignorome.
Pandey AK, et al. PLoS One 9, e88889 (2014).
Identification of two new members of the CSMD gene family.
Lau WL & Scholnick SB. Genomics 82, 412-5 (2003).
Genome-wide association study of periodontal pathogen colonization.
Divaris K, et al. J Dent Res 91, 21S-28S (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CUB (cl00049)
  CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
CCP (cl00043)
  SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Csmd3 includes H.sapiens CSMD3.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Actinopterygii - bony fishes (8 transcripts, 3 species)
Mammalia - mammals (5 transcripts, 5 species)
Aves - birds (1 transcript, 1 species)




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