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HomoloGene:55831. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ROR2,  H.sapiens
receptor tyrosine kinase-like orphan receptor 2
NP_004551.2
943 aa
ROR2,  P.troglodytes
receptor tyrosine kinase-like orphan receptor 2
XP_520126.2
948 aa
ROR2,  M.mulatta
receptor tyrosine kinase-like orphan receptor 2
XP_001105737.1
946 aa
ROR2,  C.lupus
receptor tyrosine kinase-like orphan receptor 2
XP_541309.3
944 aa
ROR2,  B.taurus
receptor tyrosine kinase-like orphan receptor 2
NP_001098934.2
940 aa
Ror2,  M.musculus
receptor tyrosine kinase-like orphan receptor 2
NP_038874.3
944 aa
Ror2,  R.norvegicus
receptor tyrosine kinase-like orphan receptor 2
NP_001100809.1
943 aa
ROR2,  G.gallus
receptor tyrosine kinase-like orphan receptor 2
NP_001074185.1
934 aa
ror2,  X.tropicalis
receptor tyrosine kinase-like orphan receptor 2
NP_001015834.1
930 aa
LOC561183,  D.rerio
tyrosine-protein kinase transmembrane receptor ROR2-like
XP_689681.6
939 aa
cam-1,  C.elegans
cam-1
NP_001021907.1
928 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Brachydactyly, type B1.
Robinow syndrome, autosomal recessive.



Publications
Articles associated with genes and sequences of this homology group.

ROR2-Related Robinow Syndrome
Bacino C, et al. (1993).
Orphan receptor kinase ROR2 is expressed in the mouse uterus.
Hatta K, et al. Placenta 31, 327-33 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
I-set (pfam07679)
  Immunoglobulin I-set domain.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
I-set (pfam07679)
  Immunoglobulin I-set domain.
DAZAP2 (pfam11029)
  DAZ associated protein 2 (DAZAP2).
KR (cl00100)
  Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
CRD_FZ (cl02447)
  CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ror2 includes H.sapiens ROR2 and R.norvegicus Ror2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 7 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

 

 

 

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