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HomoloGene:53435. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MYO18B,  H.sapiens
myosin XVIIIB
NP_115997.5
2567 aa
MYO18B,  P.troglodytes
myosin XVIIIB
XP_003953901.1
2426 aa
MYO18B,  M.mulatta
myosin XVIIIB
XP_002798363.1
1507 aa
MYO18B,  C.lupus
myosin XVIIIB
XP_543454.3
2560 aa
MYO18B,  B.taurus
myosin XVIIIB
XP_002694662.2
2837 aa
Myo18b,  M.musculus
myosin XVIIIb
NP_083177.2
2605 aa
Myo18b,  R.norvegicus
myosin XVIIIb
XP_006249639.1
2551 aa
MYO18B,  G.gallus
myosin XVIIIB
XP_415196.4
2380 aa
myo18b,  X.tropicalis
myosin XVIIIB
XP_002932132.2
2116 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Genetic alterations responsible for metastatic phenotypes of lung cancer cells.
Yokota J, et al. Clin Exp Metastasis 20, 189-93 (2003).
HOMER2 binds MYO18B and enhances its activity to suppress anchorage independent growth.
Ajima R, et al. Biochem Biophys Res Commun 356, 851-6 (2007).
A genome-wide association study of serum uric acid in African Americans.
Charles BA, et al. BMC Med Genomics 4, 17 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DUF1640 (pfam07798)
  Protein of unknown function (DUF1640).
TMF_TATA_bd (pfam12325)
  TATA element modulatory factor 1 TATA binding.
Mnd1 (pfam03962)
  Mnd1 family.
Axin_TNKS_binding (cd11582)
  Tankyrase binding N-terminal segment of axin.
Motor_domain (cl00286)
  Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes.
BASP1 (pfam05466)
  Brain acid soluble protein 1 (BASP1 protein).
DUF972 (pfam06156)
  Protein of unknown function (DUF972).
Tho2 (pfam11262)
  Transcription factor/nuclear export subunit protein 2.
TMF_TATA_bd (pfam12325)
  TATA element modulatory factor 1 TATA binding.
Motor_domain (cl00286)
  Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes.
Prefoldin (cl09111)
  Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.
Collagen (cl19732)
  Collagen triple helix repeat (20 copies).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Myo18b includes H.sapiens MYO18B and R.norvegicus Myo18b.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (5 transcripts, 5 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)

 

 

 

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