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HomoloGene:36269. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ALG12,  H.sapiens
ALG12, alpha-1,6-mannosyltransferase
NP_077010.1
488 aa
ALG12,  P.troglodytes
asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)
XP_001140006.1
488 aa
LOC715172,  M.mulatta
dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase-like
XP_002798466.1
355 aa
ALG12,  C.lupus
ALG12, alpha-1,6-mannosyltransferase
XP_005625791.1
491 aa
ALG12,  B.taurus
asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)
NP_001096816.1
491 aa
Alg12,  M.musculus
asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase)
NP_001135829.1
486 aa
Alg12,  R.norvegicus
asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase
NP_001101574.2
488 aa
ALG12,  G.gallus
asparagine-linked glycosylation 12, alpha-1,6-mannosyltransferase homolog (S. cerevisiae)
NP_001034359.2
490 aa
alg12,  X.tropicalis
ALG12, alpha-1,6-mannosyltransferase
NP_001016120.1
489 aa
alg12,  D.rerio
asparagine-linked glycosylation 12 homolog (yeast, alpha-1,6-mannosyltransferase)
NP_001092219.1
493 aa
CG8412,  D.melanogaster
CG8412
NP_649939.1
678 aa
AgaP_AGAP000102,  A.gambiae
AgaP_AGAP000102
XP_311046.4
722 aa
CELE_ZC513.5,  C.elegans
CELE_ZC513.5
NP_505071.1
492 aa
ALG12,  A.thaliana
ALG12
NP_001077448.1
497 aa
Os04g0544900,  O.sativa
Os04g0544900
NP_001053463.1
497 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Congenital disorder of glycosylation, type Ig.



Publications
Articles associated with genes and sequences of this homology group.

ALG12 mannosyltransferase defect in congenital disorder of glycosylation type lg.
Grubenmann CE, et al. Hum Mol Genet 11, 2331-9 (2002).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PMT_2 (cl15769)
  Dolichyl-phosphate-mannose-protein mannosyltransferase.
Glyco_transf_22 (cl17751)
  Alg9-like mannosyltransferase family.
Glyco_transf_22 (cl17751)
  Alg9-like mannosyltransferase family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Alg12 includes H.sapiens ALG12.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Aves - birds (4 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (11 transcripts, 8 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (14 transcripts, 12 species)
Liliopsida - monocots (8 transcripts, 8 species)
Coniferopsida - conifers (2 transcripts, 2 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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