Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:4772. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

IGF2BP1,  H.sapiens
insulin-like growth factor 2 mRNA binding protein 1
NP_006537.3
577 aa
IGF2BP1,  P.troglodytes
insulin-like growth factor 2 mRNA binding protein 1
XP_511944.2
577 aa
IGF2BP1,  M.mulatta
insulin-like growth factor 2 mRNA binding protein 1
XP_001091611.1
577 aa
IGF2BP1,  C.lupus
insulin-like growth factor 2 mRNA binding protein 1
XP_005624680.1
576 aa
IGF2BP1,  B.taurus
insulin-like growth factor 2 mRNA binding protein 1
NP_001179383.1
577 aa
Igf2bp1,  M.musculus
insulin-like growth factor 2 mRNA binding protein 1
NP_034081.1
577 aa
Igf2bp1,  R.norvegicus
insulin-like growth factor 2 mRNA binding protein 1
NP_783184.1
577 aa
IGF2BP1,  G.gallus
insulin-like growth factor 2 mRNA binding protein 1
NP_990402.1
576 aa
igf2bp1,  D.rerio
insulin-like growth factor 2 mRNA binding protein 1
NP_001070027.1
598 aa
Imp,  D.melanogaster
IGF-II mRNA-binding protein
NP_001036268.2
631 aa
AgaP_AGAP012103,  A.gambiae
AgaP_AGAP012103
XP_320427.3
494 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

IGF2BP1: a post-transcriptional "driver" of tumor cell migration.
Stöhr N & Hüttelmaier S. Cell Adh Migr 6, 312-8 (2012).
Overexpression of mRNA-binding protein CRD-BP in malignant melanomas.
Elcheva I, et al. Oncogene 27, 5069-74 (2008).
ZBP1 enhances cell polarity and reduces chemotaxis.
Lapidus K, et al. J Cell Sci 120, 3173-8 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RRM_SF (cl17169)
  RNA recognition motif (RRM) superfamily.
RRM_SF (cl17169)
  RNA recognition motif (RRM) superfamily.
KH-I (cl17245)
  K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Igf2bp1 includes H.sapiens IGF2BP1 and R.norvegicus Igf2bp1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 6 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 8 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

 

 

 

Support Center