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HomoloGene:1208. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

IRF3,  H.sapiens
interferon regulatory factor 3
NP_001562.1
427 aa
IRF3,  M.mulatta
interferon regulatory factor 3
NP_001129269.1
422 aa
IRF3,  B.taurus
interferon regulatory factor 3
NP_001025016.1
417 aa
Irf3,  M.musculus
interferon regulatory factor 3
NP_058545.1
419 aa
Irf3,  R.norvegicus
interferon regulatory factor 3
NP_001006970.1
421 aa
LOC100493780,  X.tropicalis
interferon regulatory factor 3-like
XP_002940288.1
470 aa
LOC100493014,  X.tropicalis
interferon regulatory factor 3-like
XP_002940284.2
413 aa
LOC101734275,  X.tropicalis
interferon regulatory factor 3-like
XP_004920503.1
246 aa
irf3,  D.rerio
interferon regulatory factor 3
NP_001137376.1
426 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Interferon regulatory factor 3 alters glioma inflammatory and invasive properties.
Tarassishin L & Lee SC. J Neurooncol 113, 185-94 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IRF-3 (pfam10401)
  Interferon-regulatory factor 3.
IRF-3 (pfam10401)
  Interferon-regulatory factor 3.
IRF (cl00096)
  Interferon Regulatory Factor (IRF); also known as tryptophan pentad repeat. The family of IRF transcription factors is important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. The ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Irf3 includes H.sapiens IRF3 and R.norvegicus Irf3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)

 

 

 

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