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HomoloGene:20189. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CHRM1,  H.sapiens
cholinergic receptor, muscarinic 1
NP_000729.2
460 aa
CHRM1,  P.troglodytes
cholinergic receptor, muscarinic 1
XP_508508.2
460 aa
CHRM1,  M.mulatta
cholinergic receptor, muscarinic 1
NP_001028117.1
460 aa
CHRM1,  C.lupus
cholinergic receptor, muscarinic 1
XP_005631654.1
460 aa
CHRM1,  B.taurus
cholinergic receptor, muscarinic 1
NP_001231538.1
460 aa
Chrm1,  M.musculus
cholinergic receptor, muscarinic 1, CNS
NP_001106167.1
460 aa
Chrm1,  R.norvegicus
cholinergic receptor, muscarinic 1
NP_542951.1
460 aa
LOC100490434,  X.tropicalis
muscarinic acetylcholine receptor M1-like
XP_004913718.1
521 aa
mAcR-60C,  D.melanogaster
muscarinic Acetylcholine Receptor 60C
NP_726440.1
788 aa
GPRMAC1,  A.gambiae
GPRMAC1
XP_314486.1
662 aa
gar-3,  C.elegans
gar-3
NP_001024236.1
611 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

D.melanogaster
The structural gene encoding a Drosophila homologue of vertebrate muscarinic acetylcholine receptor (mAChR). When expressed in Y1 adrenal cells it is physiologically active as measured by agonist- dependent stimulation of phosphatidylinositol metabolism.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Chrm1 includes H.sapiens CHRM1 and R.norvegicus Chrm1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

 

 

 

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