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HomoloGene:1554. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GFAP,  H.sapiens
glial fibrillary acidic protein
NP_002046.1
432 aa
GFAP,  P.troglodytes
glial fibrillary acidic protein
XP_511561.3
502 aa
GFAP,  M.mulatta
glial fibrillary acidic protein
XP_001102095.2
459 aa
GFAP,  C.lupus
glial fibrillary acidic protein
XP_848378.1
433 aa
GFAP,  B.taurus
glial fibrillary acidic protein
NP_776490.2
428 aa
Gfap,  M.musculus
glial fibrillary acidic protein
NP_034407.2
430 aa
Gfap,  R.norvegicus
glial fibrillary acidic protein
NP_058705.2
430 aa
GFAP,  G.gallus
glial fibrillary acidic protein
XP_418091.2
422 aa
gfap,  D.rerio
glial fibrillary acidic protein
NP_571448.2
444 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Alexander disease.



Publications
Articles associated with genes and sequences of this homology group.

High plasma-GFAP levels in metastatic myxopapillary ependymoma.
Ilhan-Mutlu A, et al. J Neurooncol 113, 359-63 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
KLRAQ (pfam10205)
  Predicted coiled-coil domain-containing protein.
Filament (pfam00038)
  Intermediate filament protein.
HAD_like (cl11391)
  Haloacid Dehalogenase-like Hydrolases.
Filament_head (pfam04732)
  Intermediate filament head (DNA binding) region.
5_nucleotid (cl17687)
  5' nucleotidase family.
Vps53_N (pfam04100)
  Vps53-like, N-terminal.
Filament_head (pfam04732)
  Intermediate filament head (DNA binding) region.
DUF4061 (pfam13270)
  Domain of unknown function (DUF4061).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gfap includes H.sapiens GFAP and R.norvegicus Gfap.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 14 species)
Actinopterygii - bony fishes (10 transcripts, 9 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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