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HomoloGene:4080. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MEF2A,  H.sapiens
myocyte enhancer factor 2A
NP_001165365.1
497 aa
MEF2A,  P.troglodytes
myocyte enhancer factor 2A
XP_003339324.1
493 aa
MEF2A,  M.mulatta
myocyte enhancer factor 2A
XP_001102793.1
495 aa
MEF2A,  C.lupus
myocyte enhancer factor 2A
XP_005618361.1
501 aa
MEF2A,  B.taurus
myocyte enhancer factor 2A
NP_001077107.1
492 aa
Mef2a,  M.musculus
myocyte enhancer factor 2A
NP_001028885.1
498 aa
Mef2a,  R.norvegicus
myocyte enhancer factor 2a
NP_001014057.1
495 aa
MEF2A,  G.gallus
myocyte enhancer factor 2A
NP_990195.1
499 aa
mef2aa,  D.rerio
myocyte enhancer factor 2aa
NP_571376.1
460 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Coronary artery disease, autosomal dominant, 1.



Publications
Articles associated with genes and sequences of this homology group.

MEF2 is an in vivo immune-metabolic switch.
Clark RI, et al. Cell 155, 435-47 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HJURP_C (pfam12347)
  Holliday junction regulator protein family C-terminal repeat.
MADS (cl00109)
  MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mef2a includes H.sapiens MEF2A.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (8 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (5 transcripts, 5 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

 

 

 

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