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HomoloGene:36024. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

IAPP,  H.sapiens
islet amyloid polypeptide
89 aa
IAPP,  P.troglodytes
islet amyloid polypeptide
89 aa
IAPP,  M.mulatta
islet amyloid polypeptide
89 aa
IAPP,  C.lupus
islet amyloid polypeptide
89 aa
Iapp,  M.musculus
islet amyloid polypeptide
93 aa
Iapp,  R.norvegicus
islet amyloid polypeptide
93 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

α-helix to β-hairpin transition of human amylin monomer.
Singh S, et al. J Chem Phys 138, 155101 (2013).
Cosolvent effects on the fibrillation reaction of human IAPP.
Seeliger J, et al. Phys Chem Chem Phys 15, 8902-7 (2013).
Amylin stimulates fatty acid esterification in 3T3-L1 adipocytes.
Miegueu P, et al. Mol Cell Endocrinol 366, 99-107 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Calc_CGRP_IAPP (pfam00214)
  Calcitonin / CGRP / IAPP family.
Calc_CGRP_IAPP (pfam00214)
  Calcitonin / CGRP / IAPP family.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Iapp includes H.sapiens IAPP and R.norvegicus Iapp.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (6 transcripts, 6 species)




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