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HomoloGene:36024. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

IAPP,  H.sapiens
islet amyloid polypeptide
NP_000406.1
89 aa
IAPP,  P.troglodytes
islet amyloid polypeptide
XP_003313854.1
89 aa
IAPP,  M.mulatta
islet amyloid polypeptide
XP_001098180.1
89 aa
IAPP,  C.lupus
islet amyloid polypeptide
NP_001003233.1
89 aa
Iapp,  M.musculus
islet amyloid polypeptide
NP_034621.1
93 aa
Iapp,  R.norvegicus
islet amyloid polypeptide
NP_036718.1
93 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

α-helix to β-hairpin transition of human amylin monomer.
Singh S, et al. J Chem Phys 138, 155101 (2013).
Cosolvent effects on the fibrillation reaction of human IAPP.
Seeliger J, et al. Phys Chem Chem Phys 15, 8902-7 (2013).
Amylin stimulates fatty acid esterification in 3T3-L1 adipocytes.
Miegueu P, et al. Mol Cell Endocrinol 366, 99-107 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Calc_CGRP_IAPP (pfam00214)
  Calcitonin / CGRP / IAPP family.
Calc_CGRP_IAPP (pfam00214)
  Calcitonin / CGRP / IAPP family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Iapp includes H.sapiens IAPP and R.norvegicus Iapp.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 6 species)

 

 

 

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