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HomoloGene:3572. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CLTC,  H.sapiens
clathrin, heavy chain (Hc)
NP_001275582.1
1679 aa
CLTC,  P.troglodytes
clathrin, heavy chain (Hc)
XP_001136053.1
1675 aa
CLTC,  M.mulatta
clathrin, heavy chain (Hc)
XP_001108647.2
1676 aa
CLTC,  C.lupus
clathrin, heavy chain (Hc)
XP_537700.2
1675 aa
CLTC,  B.taurus
clathrin, heavy chain (Hc)
NP_776448.1
1675 aa
Cltc,  M.musculus
clathrin, heavy polypeptide (Hc)
NP_001003908.1
1675 aa
Cltc,  R.norvegicus
clathrin, heavy chain (Hc)
NP_062172.1
1675 aa
CLTC,  G.gallus
clathrin, heavy chain (Hc)
NP_001073586.1
1675 aa
cltc,  X.tropicalis
clathrin, heavy chain (Hc)
NP_001011039.1
1675 aa
cltca,  D.rerio
clathrin, heavy polypeptide a (Hc)
NP_001005391.2
1680 aa
cltcb,  D.rerio
clathrin, heavy polypeptide b (Hc)
NP_001181907.1
1677 aa
Chc,  D.melanogaster
Clathrin heavy chain
NP_996451.1
1678 aa
AgaP_AGAP003021,  A.gambiae
AgaP_AGAP003021
XP_311856.3
1676 aa
chc-1,  C.elegans
chc-1
NP_499260.1
1681 aa
CHC1,  S.cerevisiae
CHC1
NP_011309.1
1653 aa
KLLA0F09911g,  K.lactis
KLLA0F09911g
XP_455531.1
1654 aa
AGOS_AER359W,  E.gossypii
AGOS_AER359W
NP_985215.2
1649 aa
chc1,  S.pombe
chc1
NP_594148.1
1666 aa
MGG_07768,  M.oryzae
MGG_07768
XP_003712981.1
1680 aa
NCU02510,  N.crassa
NCU02510
XP_965641.1
1678 aa
AT3G08530,  A.thaliana
AT3G08530
NP_187466.4
1703 aa
AT3G11130,  A.thaliana
AT3G11130
NP_187724.2
1705 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Clathrin is required for postmitotic Golgi reassembly.
Radulescu AE & Shields D. FASEB J 26, 129-36 (2012).
AFM visualization of clathrin triskelia under fluid and in air.
Kotova S, et al. FEBS Lett 584, 44-8 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Clathrin-link (pfam09268)
  Clathrin, heavy-chain linker.
Clathrin_H_link (pfam13838)
  Clathrin-H-link.
Clathrin (pfam00637)
  Region in Clathrin and VPS.
Clathrin_propel (pfam01394)
  Clathrin propeller repeat.
Clathrin_propel (pfam01394)
  Clathrin propeller repeat.
Clathrin-link (pfam09268)
  Clathrin, heavy-chain linker.
Clathrin_H_link (pfam13838)
  Clathrin-H-link.
Clathrin (cl19570)
  Region in Clathrin and VPS.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cltc includes H.sapiens CLTC and R.norvegicus Cltc.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (48 transcripts, 10 species)
Mammalia - mammals (28 transcripts, 17 species)
Aves - birds (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (15 transcripts, 13 species)
Arachnida - arachnids (4 transcripts, 2 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (4 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (4 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)
Hydrozoa - hydrozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (2 transcripts, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Streptophyta
Eudicotyledons - eudicots (88 transcripts, 30 species)
Liliopsida - monocots (25 transcripts, 9 species)
Coniferopsida - conifers (5 transcripts, 3 species)
Bryopsida - mosses (3 transcripts, 1 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Ascomycota
Sordariomycetes - ascomycetes (8 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Oomycetes
Pythiales - oomycetes (3 transcripts, 1 species)
Peronosporales - oomycetes (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (2 transcripts, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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