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HomoloGene:5980. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PRPF31,  H.sapiens
pre-mRNA processing factor 31
NP_056444.3
499 aa
PRPF31,  P.troglodytes
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
XP_001174769.1
499 aa
PRPF31,  M.mulatta
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
XP_001116111.2
499 aa
PRPF31,  C.lupus
pre-mRNA processing factor 31
XP_850917.1
499 aa
PRPF31,  B.taurus
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
NP_001193214.1
499 aa
Prpf31,  M.musculus
PRP31 pre-mRNA processing factor 31 homolog (yeast)
NP_081604.3
499 aa
Prpf31,  R.norvegicus
pre-mRNA processing factor 31
NP_001099689.1
499 aa
prpf31,  X.tropicalis
pre-mRNA processing factor 31
NP_998859.1
498 aa
prpf31,  D.rerio
PRP31 pre-mRNA processing factor 31 homolog (yeast)
NP_956798.1
508 aa
Prp31,  D.melanogaster
Prp31
NP_648756.1
501 aa
AgaP_AGAP012142,  A.gambiae
AgaP_AGAP012142
XP_320385.4
516 aa
prp-31,  C.elegans
prp-31
NP_491527.1
504 aa
prp31,  S.pombe
prp31
NP_595294.1
518 aa
MGG_13154,  M.oryzae
MGG_13154
XP_003710621.1
596 aa
NCU02716,  N.crassa
NCU02716
XP_965101.1
611 aa
emb1220,  A.thaliana
emb1220
NP_564754.1
485 aa
Os04g0555400,  O.sativa
Os04g0555400
NP_001053516.1
484 aa
Os07g0141600,  O.sativa
Os07g0141600
NP_001058865.1
484 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Retinitis pigmentosa-11.



Publications
Articles associated with genes and sequences of this homology group.

A 112 kb deletion in chromosome 19q13.42 leads to retinitis pigmentosa.
Rose AM, et al. Invest Ophthalmol Vis Sci 52, 6597-603 (2011).
PRPF31 alternative splicing and expression in human retina.
Tanackovic G & Rivolta C. Ophthalmic Genet 30, 76-83 (2009).
Two trans-acting eQTLs modulate the penetrance of PRPF31 mutations.
Rio Frio T, et al. Hum Mol Genet 17, 3154-65 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NOSIC (pfam08060)
  NOSIC (NUC001) domain.
Nop (pfam01798)
  Putative snoRNA binding domain.
Prp31_C (pfam09785)
  Prp31 C terminal domain.
Nop (pfam01798)
  Putative snoRNA binding domain.
Prp31_C (pfam09785)
  Prp31 C terminal domain.
NOSIC (cl06890)
  NOSIC (NUC001) domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prpf31 includes H.sapiens PRPF31 and R.norvegicus Prpf31.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (16 transcripts, 12 species)
Actinopterygii - bony fishes (9 transcripts, 9 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 12 species)
Arachnida - arachnids (3 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (43 transcripts, 31 species)
Liliopsida - monocots (14 transcripts, 9 species)
Coniferopsida - conifers (2 transcripts, 2 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)
Bryopsida - mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Oomycetes
Pythiales - oomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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