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HomoloGene:56835. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MOV10L1,  H.sapiens
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
NP_061868.1
1211 aa
MOV10L1,  P.troglodytes
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
XP_003317366.2
1214 aa
LOC720612,  M.mulatta
putative helicase Mov10l1-like
XP_002808016.1
1139 aa
MOV10L1,  C.lupus
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
XP_005625776.1
1181 aa
MOV10L1,  B.taurus
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
XP_005207609.1
1195 aa
Mov10l1,  M.musculus
Moloney leukemia virus 10-like 1
NP_112550.2
1187 aa
Mov10l1,  R.norvegicus
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
XP_006242312.1
1194 aa
MOV10L1,  G.gallus
Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
XP_003640393.2
1202 aa
mov10l1,  X.tropicalis
Mov10l1, Moloney leukemia virus 10-like 1, homolog
NP_001072624.1
1244 aa
zgc:154086,  D.rerio
zgc:154086
NP_001070795.1
1106 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

MOV10 RNA helicase is a potent inhibitor of retrotransposition in cells.
Goodier JL, et al. PLoS Genet 8, e1002941 (2012).
Helicase structure and mechanism.
Caruthers JM & McKay DB. Curr Opin Struct Biol 12, 123-33 (2002).
CHAMP, a novel cardiac-specific helicase regulated by MEF2C.
Liu ZP, et al. Dev Biol 234, 497-509 (2001).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AAA_11 (pfam13086)
  AAA domain.
AAA_12 (pfam13087)
  AAA domain.
AAA_11 (pfam13086)
  AAA domain.
AAA_12 (pfam13087)
  AAA domain.
DEXDc (cl17251)
  DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
AAA (cl18944)
  The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mov10l1 includes H.sapiens MOV10L1 and R.norvegicus Mov10l1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 8 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 4 species)
Arachnida - arachnids (3 transcripts, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (2 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (3 transcripts, 3 species)
Liliopsida - monocots (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Ascomycota
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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