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HomoloGene:84397. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

NR2E3,  H.sapiens
nuclear receptor subfamily 2, group E, member 3
NP_055064.1
410 aa
NR2E3,  P.troglodytes
nuclear receptor subfamily 2, group E, member 3
XP_001175025.1
402 aa
NR2E3,  M.mulatta
nuclear receptor subfamily 2, group E, member 3
XP_001089693.1
448 aa
NR2E3,  B.taurus
nuclear receptor subfamily 2, group E, member 3
NP_001161372.1
411 aa
Nr2e3,  M.musculus
nuclear receptor subfamily 2, group E, member 3
NP_038736.1
395 aa
LOC100365683,  R.norvegicus
nuclear receptor subfamily 2, group E, member 3-like
XP_003750575.2
294 aa
NR2E3,  G.gallus
nuclear receptor subfamily 2, group E, member 3
NP_989925.1
406 aa
nr2e3,  X.tropicalis
nuclear receptor subfamily 2, group E, member 3
NP_001090633.1
404 aa
nr2e3,  D.rerio
nuclear receptor subfamily 2, group E, member 3
NP_001007369.1
419 aa
Hr51,  D.melanogaster
Hormone receptor 51
NP_611032.2
582 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Enhanced S-cone syndrome.
Retinitis pigmentosa-37.



Publications
Articles associated with genes and sequences of this homology group.

Novel mutations in enhanced S-cone syndrome.
Kuniyoshi K, et al. Ophthalmology 120, 431.e1-6 (2013).
A novel mutation (Cys83Tyr) in the second zinc finger of NR2E3 in enhanced S-cone syndrome.
Rocha-Sousa A, et al. Graefes Arch Clin Exp Ophthalmol 249, 201-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nr2e3 includes H.sapiens NR2E3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (3 transcripts, 3 species)
Actinopterygii - bony fishes (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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