Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:23186. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MBNL1,  H.sapiens
muscleblind-like splicing regulator 1
NP_997176.1
388 aa
MBNL1,  P.troglodytes
muscleblind-like splicing regulator 1
XP_516823.3
388 aa
MBNL1,  M.mulatta
muscleblind-like splicing regulator 1
XP_001106579.2
387 aa
MBNL1,  C.lupus
muscleblind-like splicing regulator 1
XP_005634633.1
399 aa
MBNL1,  B.taurus
muscleblind-like splicing regulator 1
NP_001093195.1
369 aa
Mbnl1,  M.musculus
muscleblind-like 1 (Drosophila)
NP_064391.2
381 aa
Mbnl1,  R.norvegicus
muscleblind-like splicing regulator 1
NP_001178495.1
387 aa
MBNL1,  G.gallus
muscleblind-like (Drosophila)
NP_001156796.1
399 aa
mbnl1,  X.tropicalis
muscleblind-like splicing regulator 1
XP_004914504.1
494 aa
mbnl1,  D.rerio
muscleblind-like (Drosophila)
NP_001093520.2
412 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3.
Gooding C, et al. Nucleic Acids Res 41, 4765-82 (2013).
RNA splicing is responsive to MBNL1 dose.
Jog SP, et al. PLoS One 7, e48825 (2012).
Sequestration of MBNL1 in tissues of patients with myotonic dystrophy type 2.
Lukáš Z, et al. Neuromuscul Disord 22, 604-16 (2012).
RNase H-mediated degradation of toxic RNA in myotonic dystrophy type 1.
Lee JE, et al. Proc Natl Acad Sci U S A 109, 4221-6 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-CCCH (cl11592)
  Abstract information not available



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mbnl1 includes H.sapiens MBNL1 and R.norvegicus Mbnl1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (11 transcripts, 6 species)
Aves - birds (3 transcripts, 3 species)
Amniota - vertebrates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 7 species)
Arachnida - arachnids (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

Support Center