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HomoloGene:1180. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HSPB1,  H.sapiens
heat shock 27kDa protein 1
NP_001531.1
205 aa
HSPB1,  P.troglodytes
heat shock 27kDa protein 1
XP_003951106.1
205 aa
HSPB1,  M.mulatta
heat shock 27kDa protein 1
XP_001109274.1
205 aa
HSPB1,  C.lupus
heat shock 27kDa protein 1
NP_001003295.1
209 aa
HSPB1,  B.taurus
heat shock 27kDa protein 1
NP_001020740.1
204 aa
Hspb1,  M.musculus
heat shock protein 1
NP_038588.2
209 aa
Hspb1,  R.norvegicus
heat shock protein 1
NP_114176.3
205 aa
HSPB1,  G.gallus
heat shock 27kDa protein 1
NP_990621.1
193 aa
hspb1,  X.tropicalis
heat shock 27kDa protein 1
NP_001072817.1
211 aa
hspb1,  D.rerio
heat shock protein, alpha-crystallin-related, 1
NP_001008615.2
199 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Charcot-Marie-Tooth disease, axonal, type 2F.
Neuropathy, distal hereditary motor, type IIB.



Publications
Articles associated with genes and sequences of this homology group.

HSPB1 facilitates the formation of non-centrosomal microtubules.
Almeida-Souza L, et al. PLoS One 8, e66541 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
alpha-crystallin-Hsps_p23-like (cl00175)
  alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hspb1 includes H.sapiens HSPB1 and R.norvegicus Hspb1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (21 transcripts, 15 species)
Actinopterygii - bony fishes (12 transcripts, 9 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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