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HomoloGene:10723. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SEPN1,  H.sapiens
selenoprotein N, 1
NP_996809.1
556 aa
SEPN1,  P.troglodytes
selenoprotein N, 1
XP_003307954.2
539 aa
SEPN1,  M.mulatta
selenoprotein N, 1
XP_002802303.1
576 aa
SEPN1,  C.lupus
selenoprotein N, 1
NP_001108447.1
504 aa
SEPN1,  B.taurus
selenoprotein N, 1
NP_001108448.1
557 aa
Sepn1,  M.musculus
selenoprotein N, 1
NP_083376.2
557 aa
Sepn1,  R.norvegicus
selenoprotein N, 1
XP_006239194.1
509 aa
SEPN1,  G.gallus
selenoprotein N, 1
NP_001108444.1
530 aa
sepn1,  X.tropicalis
selenoprotein N, 1
NP_001070901.1
562 aa
sepn1,  D.rerio
selenoprotein N, 1
NP_001004294.4
557 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Muscular dystrophy, rigid spine, 1.



Publications
Articles associated with genes and sequences of this homology group.

Selenoprotein N in skeletal muscle: from diseases to function.
Castets P, et al. J Mol Med (Berl) 90, 1095-107 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
glgC (PRK02862)
  glucose-1-phosphate adenylyltransferase; Provisional.
EFh (cd00051)
  EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Sepn1 includes H.sapiens SEPN1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Aves - birds (3 transcripts, 3 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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