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HomoloGene:55823. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ENDOG,  H.sapiens
endonuclease G
NP_004426.2
297 aa
ENDOG,  P.troglodytes
endonuclease G
XP_003312364.2
348 aa
LOC717171,  M.mulatta
endonuclease G, mitochondrial-like
XP_001110294.1
299 aa
ENDOG,  C.lupus
endonuclease G
XP_851160.2
439 aa
ENDOG,  B.taurus
endonuclease G
NP_787017.1
299 aa
Endog,  M.musculus
endonuclease G
NP_031957.1
294 aa
Endog,  R.norvegicus
endonuclease G
NP_001030110.1
294 aa
LOC100859613,  G.gallus
endonuclease G, mitochondrial-like
XP_004945896.1
301 aa
ENDOG,  G.gallus
endonuclease G
XP_415487.2
301 aa
endog,  X.tropicalis
endonuclease G
NP_001017202.1
293 aa
endog,  D.rerio
endonuclease G
NP_001019385.1
306 aa
EndoG,  D.melanogaster
Endonuclease G
NP_610737.1
310 aa
AgaP_AGAP007845,  A.gambiae
AgaP_AGAP007845
XP_317654.4
323 aa
cps-6,  C.elegans
cps-6
NP_491371.1
308 aa
NUC1,  S.cerevisiae
NUC1
NP_012327.1
329 aa
KLLA0D00440g,  K.lactis
KLLA0D00440g
XP_453091.1
332 aa
AGOS_ADR144C,  E.gossypii
AGOS_ADR144C
NP_984240.1
295 aa
pnu1,  S.pombe
pnu1
NP_594598.2
322 aa
MGG_05324,  M.oryzae
MGG_05324
XP_003712888.1
333 aa
NCU00030,  N.crassa
NCU00030
XP_957017.1
332 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Endonuclease G mediates endothelial cell death induced by carbamylated LDL.
Apostolov EO, et al. Am J Physiol Heart Circ Physiol 300, H1997-2004 (2011).
Purification, crystallization and data collection of the apoptotic nuclease endonuclease G.
Yoon SM, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun 65, 504-7 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NUC (cl00089)
  DNA/RNA non-specific endonuclease; prokaryotic and eukaryotic double- and single-stranded DNA and RNA endonucleases also present in phosphodiesterases. They exists as monomers and homodimers.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Endog includes H.sapiens ENDOG and R.norvegicus Endog.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (8 transcripts, 6 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)

Arthropoda
Insecta - insects (7 transcripts, 7 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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