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HomoloGene:22589. Gene conserved in Bilateria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

KIF13A,  H.sapiens
kinesin family member 13A
1805 aa
KIF13A,  P.troglodytes
kinesin family member 13A
1805 aa
KIF13A,  M.mulatta
kinesin family member 13A
1809 aa
KIF13A,  C.lupus
kinesin family member 13A
1750 aa
KIF13A,  B.taurus
kinesin family member 13A
1734 aa
Kif13a,  M.musculus
kinesin family member 13A
1749 aa
Kif13a,  R.norvegicus
kinesin family member 13A
1689 aa
KIF13A,  G.gallus
kinesin family member 13A
1987 aa
kif13a,  X.tropicalis
kinesin family member 13A
1967 aa
kif13a,  D.rerio
kinesin family member 13A
1869 aa
AgaP_AGAP007592,  A.gambiae
1944 aa
klp-4,  C.elegans
1576 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Gadkin: A novel link between endosomal vesicles and microtubule tracks.
Maritzen T & Haucke V. Commun Integr Biol 3, 299-302 (2010).
Abscission accomplished by PtdIns(3)P.
Montagnac G & Chavrier P. Nat Cell Biol 12, 308-10 (2010).
It takes two to tango to the melanosome.
Lakkaraju A, et al. J Cell Biol 187, 161-3 (2009).
Kinesin-73 in the nervous system of Drosophila embryos.
Li HP, et al. Proc Natl Acad Sci U S A 94, 1086-91 (1997).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PEPcase (cl14656)
  Phosphoenolpyruvate carboxylase.
CAP_GLY (pfam01302)
  CAP-Gly domain.
DUF3585 (pfam12130)
  Protein of unknown function (DUF3585).
KIF1B (pfam12423)
  Kinesin protein 1B.
DUF3694 (pfam12473)
  Kinesin protein.
KIF1B (pfam12423)
  Kinesin protein 1B.
DUF3694 (pfam12473)
  Kinesin protein.
FHA (cl00062)
  Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).
Motor_domain (cl00286)
  Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Kif13a includes H.sapiens KIF13A and R.norvegicus Kif13a.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (7 transcripts, 3 species)
Ascidiacea - tunicates (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Insecta - insects (4 transcripts, 3 species)
Arachnida - arachnids (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Chromadorea - nematodes (2 transcripts, 2 species)

Hydrozoa - hydrozoans (1 transcript, 1 species)

Polychaeta - segmented worms (1 transcript, 1 species)




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