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HomoloGene:1836. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MSX1,  H.sapiens
msh homeobox 1
NP_002439.2
303 aa
MSX1,  P.troglodytes
msh homeobox 1
NP_001182191.1
303 aa
MSX1,  M.mulatta
msh homeobox 1
XP_001118871.2
530 aa
MSX1,  C.lupus
msh homeobox 1
XP_545946.2
236 aa
MSX1,  B.taurus
msh homeobox 1
NP_777223.1
297 aa
Msx1,  M.musculus
msh homeobox 1
NP_034965.2
303 aa
Msx1,  R.norvegicus
msh homeobox 1
NP_112321.1
297 aa
MSX1,  G.gallus
msh homeobox 1
NP_990819.1
288 aa
msx1,  X.tropicalis
msh homeobox 1
NP_001032329.1
275 aa
msxe,  D.rerio
muscle segment homeobox E
NP_571348.1
233 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hypodontia with orofacial cleft.
Hypodontia, autosomal dominant.
Witkop syndrome.
Cleft lip/palate, nonsyndromic.



Publications
Articles associated with genes and sequences of this homology group.

Polymorphism in the MSX1 gene in a family with upper lateral incisor agenesis.
Boeira Junior BR & Echeverrigaray S. Arch Oral Biol 57, 1423-8 (2012).
Transcriptional regulation of MSX1 natural antisense transcript.
Babajko S, et al. Cells Tissues Organs 194, 151-5 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
homeodomain (cl00084)
  Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Msx1 includes H.sapiens MSX1 and R.norvegicus Msx1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 7 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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