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HomoloGene:20698. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TLR5,  H.sapiens
toll-like receptor 5
NP_003259.2
858 aa
TLR5,  P.troglodytes
toll-like receptor 5
NP_001123934.1
858 aa
TLR5,  M.mulatta
toll-like receptor 5
NP_001123901.1
858 aa
TLR5,  C.lupus
toll-like receptor 5
NP_001184105.1
858 aa
TLR5,  B.taurus
toll-like receptor 5
NP_001035591.1
858 aa
Tlr5,  M.musculus
toll-like receptor 5
NP_058624.2
873 aa
Tlr5,  R.norvegicus
toll-like receptor 5
NP_001139300.1
871 aa
TLR5,  G.gallus
toll-like receptor 5
NP_001019757.1
861 aa
LOC100496647,  X.tropicalis
toll-like receptor 5-like
XP_002940742.2
879 aa
tlr5b,  D.rerio
toll-like receptor 5b
NP_001124067.1
875 aa
tlr5a,  D.rerio
toll-like receptor 5a
XP_001919052.2
881 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Systemic lupus erythematosus, resistance to.
Systemic lupus erythematosus, susceptibility to, 1.
Legionaire disease, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Central role of liver in anticancer and radioprotective activities of Toll-like receptor 5 agonist.
Burdelya LG, et al. Proc Natl Acad Sci U S A 110, E1857-66 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LRR_TYP (cl15310)
  Leucine-rich repeats, typical (most populated) subfamily.
LRR_4 (pfam12799)
  Leucine Rich repeats (2 copies).
LRR_8 (pfam13855)
  Leucine rich repeat.
LRRCT (smart00082)
  Leucine rich repeat C-terminal domain.
TIR (pfam01582)
  TIR domain.
LRR_8 (pfam13855)
  Leucine rich repeat.
TIR_2 (cl17458)
  TIR domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tlr5 includes H.sapiens TLR5 and R.norvegicus Tlr5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)
Actinopterygii - bony fishes (2 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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