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HomoloGene:20916. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CD151,  H.sapiens
CD151 molecule (Raph blood group)
NP_620598.1
253 aa
CD151,  P.troglodytes
CD151 molecule (Raph blood group)
XP_001151340.1
253 aa
CD151,  M.mulatta
CD151 molecule (Raph blood group)
NP_001027994.1
253 aa
CD151,  C.lupus
CD151 molecule (Raph blood group)
XP_533198.1
252 aa
CD151,  B.taurus
CD151 molecule (Raph blood group)
NP_001030424.1
253 aa
Cd151,  M.musculus
CD151 antigen
NP_001104520.1
253 aa
Cd151,  R.norvegicus
CD151 molecule (Raph blood group)
NP_071968.1
253 aa
LOC100911730,  R.norvegicus
CD151 antigen-like
XP_003749065.1
253 aa
CD151,  G.gallus
CD151 molecule (Raph blood group)
NP_001006472.1
252 aa
cd151,  X.tropicalis
CD151 molecule (Raph blood group)
NP_001116919.1
253 aa
cd151l,  D.rerio
CD151 antigen, like
NP_991213.1
254 aa
Tsp74F,  D.melanogaster
Tetraspanin 74F
NP_730317.1
236 aa
AgaP_AGAP011342,  A.gambiae
AgaP_AGAP011342
XP_309308.4
233 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Blood group, Raph.
Nephropathy with pretibial epidermolysis bullosa and deafness.



Publications
Articles associated with genes and sequences of this homology group.

CD151 in cancer progression and metastasis: a complex scenario.
Sadej R, et al. Lab Invest 94, 41-51 (2014).
Tetraspanin CD151 mediates papillomavirus type 16 endocytosis.
Scheffer KD, et al. J Virol 87, 3435-46 (2013).
Diminished metastasis in tetraspanin CD151-knockout mice.
Takeda Y, et al. Blood 118, 464-72 (2011).
Tetraspanin CD151 as a target for antibody-based cancer immunotherapy.
Haeuw JF, et al. Biochem Soc Trans 39, 553-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
tetraspanin_LEL (cl02781)
  Tetraspanin, extracellular domain or large extracellular loop (LEL). Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model spans the ...
SLC5-6-like_sbd (cl00456)
  Solute carrier families 5 and 6-like; solute binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cd151 includes H.sapiens CD151 and R.norvegicus Cd151.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 13 species)
Actinopterygii - bony fishes (14 transcripts, 9 species)
Ascidiacea - tunicates (3 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (4 transcripts, 3 species)
Arachnida - arachnids (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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