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HomoloGene:38160. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PRKAB1,  H.sapiens
protein kinase, AMP-activated, beta 1 non-catalytic subunit
NP_006244.2
270 aa
PRKAB1,  P.troglodytes
protein kinase, AMP-activated, beta 1 non-catalytic subunit
NP_001233530.1
270 aa
PRKAB1,  M.mulatta
protein kinase, AMP-activated, beta 1 non-catalytic subunit
XP_001085323.1
270 aa
PRKAB1,  C.lupus
protein kinase, AMP-activated, beta 1 non-catalytic subunit
XP_543421.2
270 aa
PRKAB1,  B.taurus
protein kinase, AMP-activated, beta 1 non-catalytic subunit
NP_001019729.1
270 aa
Prkab1,  M.musculus
protein kinase, AMP-activated, beta 1 non-catalytic subunit
NP_114075.1
270 aa
Prkab1,  R.norvegicus
protein kinase, AMP-activated, beta 1 non-catalytic subunit
NP_114182.1
270 aa
PRKAB1,  G.gallus
protein kinase, AMP-activated, beta 1 non-catalytic subunit
NP_001035001.1
273 aa
prkab1,  X.tropicalis
protein kinase, AMP-activated, beta 1 non-catalytic subunit
XP_002932123.1
265 aa
prkab1a,  D.rerio
protein kinase, AMP-activated, beta 1 non-catalytic subunit, a
NP_001002632.1
268 aa
alc,  D.melanogaster
alicorn
NP_610460.1
341 aa
AgaP_AGAP008195,  A.gambiae
AgaP_AGAP008195
XP_317273.3
297 aa
amk2,  S.pombe
amk2
NP_588485.1
298 aa
MGG_06930,  M.oryzae
MGG_06930
XP_003709669.1
479 aa
NCU03837,  N.crassa
NCU03837
XP_960596.1
481 aa
AT4G16360,  A.thaliana
AT4G16360
NP_001031650.2
258 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

A role for AMPK in increased insulin action after serum starvation.
Ching JK, et al. Am J Physiol Cell Physiol 299, C1171-9 (2010).
The role of AMP-activated protein kinase in the cardiovascular system.
Nagata D & Hirata Y. Hypertens Res 33, 22-8 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AMPKBI (pfam04739)
  5'-AMP-activated protein kinase beta subunit, interation domain.
AMPKBI (cl08426)
  5'-AMP-activated protein kinase beta subunit, interation domain.
E_set (cl09101)
  Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Prkab1 includes H.sapiens PRKAB1 and R.norvegicus Prkab1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (9 transcripts, 7 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (17 transcripts, 13 species)
Arachnida - arachnids (3 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (40 transcripts, 27 species)
Bryopsida - mosses (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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