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HomoloGene:37827. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GEMIN2,  H.sapiens
gem (nuclear organelle) associated protein 2
NP_003607.1
280 aa
SIP1,  P.troglodytes
survival of motor neuron protein interacting protein 1
XP_509917.1
280 aa
SIP1,  M.mulatta
gem (nuclear organelle) associated protein 2
XP_001092707.1
269 aa
GEMIN2,  C.lupus
gem (nuclear organelle) associated protein 2
XP_005623408.1
269 aa
GEMIN2,  B.taurus
gem (nuclear organelle) associated protein 2
XP_003587627.1
280 aa
Gemin2,  M.musculus
gem (nuclear organelle) associated protein 2
NP_079932.2
269 aa
Gemin2,  R.norvegicus
gem (nuclear organelle) associated protein 2
NP_445841.1
269 aa
GEMIN2,  G.gallus
gem (nuclear organelle) associated protein 2
NP_001034391.1
263 aa
gemin2,  X.tropicalis
gem (nuclear organelle) associated protein 2
NP_001096228.1
267 aa
gemin2,  D.rerio
gem (nuclear organelle) associated protein 2
NP_001017608.1
253 aa
Gem2,  D.melanogaster
Gemin2
NP_649092.1
245 aa
AgaP_AGAP005413,  A.gambiae
AgaP_AGAP005413
XP_001688660.1
282 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The gemin2-binding site on SMN protein: accessibility to antibody.
Lam le T, et al. Biochem Biophys Res Commun 438, 624-7 (2013).
[Coding-sequence point mutation and polymorphism analyses of SIP1 gene in Hirschsprung disease].
Gao H, et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25, 82-5 (2008).
Increased expression level of the splicing variant of SIP1 in motor neuron diseases.
Aerbajinai W, et al. Int J Biochem Cell Biol 34, 699-707 (2002).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SIP1 (pfam04938)
  Survival motor neuron (SMN) interacting protein 1 (SIP1).
SIP1 (pfam04938)
  Survival motor neuron (SMN) interacting protein 1 (SIP1).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gemin2 includes H.sapiens GEMIN2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (9 transcripts, 8 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (6 transcripts, 5 species)
Arachnida - arachnids (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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