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HomoloGene:1159. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GTF2H2,  H.sapiens
general transcription factor IIH, polypeptide 2, 44kDa
NP_001506.1
395 aa
GTF2H2,  P.troglodytes
general transcription factor IIH, polypeptide 2, 44kDa
XP_001158018.1
395 aa
GTF2H2,  M.mulatta
general transcription factor IIH, polypeptide 2, 44kDa
XP_002804450.1
395 aa
GTF2H2,  C.lupus
general transcription factor IIH, polypeptide 2, 44kDa
XP_535266.2
395 aa
GTF2H2,  B.taurus
general transcription factor IIH, polypeptide 2, 44kDa
NP_001033619.1
395 aa
Gtf2h2,  M.musculus
general transcription factor II H, polypeptide 2
NP_071294.3
396 aa
Gtf2h2,  R.norvegicus
general transcription factor IIH, polypeptide 2
NP_001070896.1
396 aa
GTF2H2,  G.gallus
general transcription factor IIH, polypeptide 2, 44kDa
XP_003643123.1
395 aa
gtf2h2,  X.tropicalis
general transcription factor IIH, polypeptide 2, 44kDa
NP_001011081.1
393 aa
gtf2h2,  D.rerio
general transcription factor IIH, polypeptide 2
NP_963875.1
392 aa
Ssl1,  D.melanogaster
Ssl1
NP_001262227.1
438 aa
AgaP_AGAP010559,  A.gambiae
AgaP_AGAP010559
XP_314533.4
421 aa
CELE_T16H12.4,  C.elegans
CELE_T16H12.4
NP_499239.1
376 aa
SSL1,  S.cerevisiae
SSL1
NP_013105.1
461 aa
KLLA0E09615g,  K.lactis
KLLA0E09615g
XP_454384.1
488 aa
AGOS_ADR338C,  E.gossypii
AGOS_ADR338C
NP_984434.1
469 aa
ssl1,  S.pombe
ssl1
NP_587800.1
421 aa
MGG_06690,  M.oryzae
MGG_06690
XP_003709398.1
516 aa
NCU01831,  N.crassa
NCU01831
XP_956615.1
416 aa
GTF2H2,  A.thaliana
GTF2H2
NP_683275.2
421 aa
Os04g0508900,  O.sativa
Os04g0508900
NP_001053274.2
173 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Impairment of alveolar macrophage transcription in idiopathic pulmonary fibrosis.
Ren P, et al. Am J Respir Crit Care Med 175, 1151-7 (2007).
Structural characterization of the cysteine-rich domain of TFIIH p44 subunit.
Fribourg S, et al. J Biol Chem 275, 31963-71 (2000).
The multiple roles of transcription/repair factor TFIIH.
Svejstrup JQ, et al. Trends Biochem Sci 21, 346-50 (1996).
The role of XPC: implications in cancer and oxidative DNA damage.
Melis JP, et al. Mutat Res 728, 107-17 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
vWFA (cl00057)
  Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
C1_4 (cl06838)
  TFIIH C1-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gtf2h2 includes H.sapiens GTF2H2 and R.norvegicus Gtf2h2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 13 species)
Actinopterygii - bony fishes (11 transcripts, 10 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 10 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (26 transcripts, 22 species)
Liliopsida - monocots (9 transcripts, 7 species)
Coniferopsida - conifers (2 transcripts, 2 species)
Bryopsida - mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

 

 

 

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