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HomoloGene:1837. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MSX2,  H.sapiens
msh homeobox 2
NP_002440.2
267 aa
MSX2,  P.troglodytes
msh homeobox 2
NP_001129097.2
267 aa
MSX2,  M.mulatta
msh homeobox 2
XP_001082405.1
267 aa
MSX2,  C.lupus
msh homeobox 2
NP_001003098.1
267 aa
MSX2,  B.taurus
msh homeobox 2
NP_001073082.1
267 aa
Msx2,  M.musculus
msh homeobox 2
NP_038629.2
267 aa
Msx2,  R.norvegicus
msh homeobox 2
NP_037114.2
267 aa
MSX2,  G.gallus
msh homeobox 2
NP_989890.1
259 aa
msx2,  X.tropicalis
msh homeobox 2
XP_002936749.1
256 aa
msxd,  D.rerio
muscle segment homeobox D
NP_571351.2
226 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Parietal foramina 1.
Parietal foramina with cleidocranial dysplasia.
Craniosynostosis, type 2.



Publications
Articles associated with genes and sequences of this homology group.

Msx2 is required for TNF-α-induced canonical Wnt signaling in 3T3-L1 preadipocytes.
Qadir AS, et al. Biochem Biophys Res Commun 408, 399-404 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
homeodomain (cl00084)
  Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Msx2 includes H.sapiens MSX2 and R.norvegicus Msx2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (3 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)
Arachnida - arachnids (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

 

 

 

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