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HomoloGene:37281. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

OCA2,  H.sapiens
oculocutaneous albinism II
NP_000266.2
838 aa
OCA2,  P.troglodytes
oculocutaneous albinism II
XP_001162129.1
838 aa
LOC712220,  M.mulatta
p protein-like
XP_002804735.1
1229 aa
LOC488683,  C.lupus
P protein-like
XP_545800.3
762 aa
LOC524289,  B.taurus
P protein-like
XP_002685246.1
831 aa
Oca2,  M.musculus
oculocutaneous albinism II
NP_068679.1
833 aa
LOC100365773,  R.norvegicus
pink-eyed dilution-like
NP_001258422.1
842 aa
OCA2,  G.gallus
oculocutaneous albinism II
XP_425579.4
851 aa
oca2,  X.tropicalis
oculocutaneous albinism II
XP_002937026.2
848 aa
oca2,  D.rerio
oculocutaneous albinism II
XP_695807.5
834 aa
AgaP_AGAP009283,  A.gambiae
AgaP_AGAP009283
XP_320079.4
663 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Albinism, brown oculocutaneous.
Albinism, ocular, autosomal recessive.
Albinism, oculocutaneous, type II.
Eye color 3.
Hair color 3.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ArsB_NhaD_permease (cl15356)
  Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...
ArsB_NhaD_permease (cl17221)
  Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...
ArsB_NhaD_permease (cl17221)
  Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Oca2 includes H.sapiens OCA2 and R.norvegicus Oca2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (6 transcripts, 4 species)
Arachnida - arachnids (3 transcripts, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

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