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HomoloGene:47922. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GLB1,  H.sapiens
galactosidase, beta 1
NP_001073279.1
647 aa
GLB1,  P.troglodytes
galactosidase, beta 1
XP_003950098.1
677 aa
LOC709355,  M.mulatta
beta-galactosidase-like
XP_001097877.1
373 aa
GLB1,  C.lupus
galactosidase, beta 1
NP_001032730.1
668 aa
GLB1,  B.taurus
galactosidase, beta 1
NP_001030215.1
653 aa
Glb1,  M.musculus
galactosidase, beta 1
NP_033882.1
647 aa
Glb1,  R.norvegicus
galactosidase, beta 1
NP_001101662.1
647 aa
GLB1,  G.gallus
galactosidase, beta 1
NP_001265076.1
652 aa
glb1l,  X.tropicalis
galactosidase, beta 1-like
NP_001015958.1
648 aa
glb1,  D.rerio
galactosidase, beta 1
NP_001017547.1
651 aa
AgaP_AGAP002056,  A.gambiae
AgaP_AGAP002056
XP_001689312.2
629 aa
T19B10.3,  C.elegans
T19B10.3
NP_505849.2
653 aa
H22K11.2,  C.elegans
H22K11.2
NP_509140.2
642 aa
BGAL17,  A.thaliana
BGAL17
NP_565051.1
697 aa
Os05g0539400,  O.sativa
Os05g0539400
NP_001056172.1
673 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
GM1-gangliosidosis.
Mucopolysaccharidosis IVB.



Publications
Articles associated with genes and sequences of this homology group.

GLB1-Related Disorders
Regier DS, et al. (1993).
Oncogene-induced senescence in pituitary adenomas and carcinomas.
Alexandraki KI, et al. Hormones (Athens) 11, 297-307 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Glyco_hydro_2_N (cl08371)
  Glycosyl hydrolases family 2, sugar binding domain.
Glyco_hydro_35 (pfam01301)
  Glycosyl hydrolases family 35.
BetaGal_dom4_5 (pfam13364)
  Beta-galactosidase jelly roll domain.
Glyco_hydro_35 (pfam01301)
  Glycosyl hydrolases family 35.
BetaGal_dom4_5 (pfam13364)
  Beta-galactosidase jelly roll domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Glb1 includes H.sapiens GLB1 and R.norvegicus Glb1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (20 transcripts, 15 species)
Actinopterygii - bony fishes (16 transcripts, 11 species)
Amphibia - amphibians (3 transcripts, 2 species)
Hyperoartia - vertebrates (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (19 transcripts, 9 species)
Arachnida - arachnids (7 transcripts, 2 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (3 transcripts, 1 species)
Hydrozoa - hydrozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (24 transcripts, 22 species)
Liliopsida - monocots (7 transcripts, 7 species)
Bryopsida - mosses (2 transcripts, 1 species)

 

 

 

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