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HomoloGene:2230. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SALL1,  H.sapiens
spalt-like transcription factor 1
NP_002959.2
1324 aa
SALL1,  P.troglodytes
sal-like 1 (Drosophila)
XP_528651.4
1226 aa
SALL1,  M.mulatta
sal-like 1 (Drosophila)
XP_001088338.2
1151 aa
SALL1,  C.lupus
sal-like 1 (Drosophila)
XP_005617623.1
1324 aa
SALL1,  B.taurus
sal-like 1 (Drosophila)
NP_001192719.1
1316 aa
Sall1,  M.musculus
sal-like 1 (Drosophila)
NP_067365.2
1323 aa
Sall1,  R.norvegicus
spalt-like transcription factor 1
NP_001100885.2
1315 aa
SALL1,  G.gallus
sal-like 1 (Drosophila)
NP_990038.1
1308 aa
sall1,  X.tropicalis
spalt-like transcription factor 1
NP_001090646.1
1330 aa
sall1a,  D.rerio
sal-like 1a (Drosophila)
NP_001139486.1
1313 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Townes-Brocks branchiootorenal-like syndrome.
Townes-Brocks syndrome.



Publications
Articles associated with genes and sequences of this homology group.

Townes-Brocks Syndrome
Kohlhase J, et al. (1993).
Kidney failure in Townes-Brocks syndrome: an under recognized phenomenon?
Reardon W, et al. Am J Med Genet A 143A, 2588-91 (2007).
Essential roles of Sall family genes in kidney development.
Nishinakamura R & Osafune K. J Physiol Sci 56, 131-6 (2006).
Defining the heterochromatin localization and repression domains of SALL1.
Netzer C, et al. Biochim Biophys Acta 1762, 386-91 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ZnF_C2H2 (smart00355)
  zinc finger.
zf-C2H2_jaz (pfam12171)
  Zinc-finger double-stranded RNA-binding.
lambda-1 (cd11674)
  inner capsid protein lambda-1 or VP3.
zf-H2C2_2 (pfam13465)
  Zinc-finger double domain.
zf-C2H2 (cl15478)
  Zinc finger, C2H2 type.
zf-C2H2 (pfam00096)
  Zinc finger, C2H2 type.
zf-H2C2_2 (cl19539)
  Zinc-finger double domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Sall1 includes H.sapiens SALL1 and R.norvegicus Sall1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)
Actinopterygii - bony fishes (9 transcripts, 5 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 2 species)
Arachnida - arachnids (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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