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HomoloGene:2916. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MBD4,  H.sapiens
methyl-CpG binding domain protein 4
NP_003916.1
580 aa
MBD4,  P.troglodytes
methyl-CpG binding domain protein 4
XP_001144095.1
580 aa
MBD4,  M.mulatta
methyl-CpG binding domain protein 4
XP_001116090.2
544 aa
MBD4,  C.lupus
methyl-CpG binding domain protein 4
XP_003432809.1
570 aa
MBD4,  B.taurus
methyl-CpG binding domain protein 4
NP_001029577.1
554 aa
Mbd4,  M.musculus
methyl-CpG binding domain protein 4
NP_034904.2
554 aa
Mbd4,  R.norvegicus
methyl-CpG binding domain protein 4
XP_001059437.3
566 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ENDO3c (cl14786)
  endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases.
MBD (cl00110)
  MeCP2, MBD1, MBD2, MBD3, MBD4, CLLD8-like, and BAZ2A-like proteins constitute a family of proteins that share the methyl-CpG-binding domain (MBD). The MBD consists of about 70 residues and is defined as the minimal region required for binding to ...
ENDO3c (cl19066)
  endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mbd4 includes H.sapiens MBD4 and R.norvegicus Mbd4.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 10 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Aves - birds (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Arthropoda
Malacostraca - crustaceans (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (2 transcripts, 2 species)
Liliopsida - monocots (2 transcripts, 2 species)

 

 

 

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