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HomoloGene:3908. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HSPA5,  H.sapiens
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
NP_005338.1
654 aa
HSPA5,  P.troglodytes
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
XP_520257.2
654 aa
HSPA5,  M.mulatta
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
XP_001099110.1
654 aa
HSPA5,  C.lupus
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
XP_863385.2
654 aa
HSPA5,  B.taurus
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
NP_001068616.1
655 aa
Hspa5,  M.musculus
heat shock protein 5
NP_001156906.1
655 aa
Hspa5,  R.norvegicus
heat shock protein 5
NP_037215.1
654 aa
HSPA5,  G.gallus
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
NP_990822.1
652 aa
LOC100492570,  X.tropicalis
78 kDa glucose-regulated protein-like
XP_002941690.1
655 aa
hspa5,  D.rerio
heat shock protein 5
NP_998223.1
650 aa
Hsc70-3,  D.melanogaster
Heat shock protein cognate 3
NP_727564.1
656 aa
AgaP_AGAP004192,  A.gambiae
AgaP_AGAP004192
XP_313085.3
659 aa
hsp-4,  C.elegans
hsp-4
NP_495536.1
657 aa
hsp-3,  C.elegans
hsp-3
NP_509019.1
661 aa
KAR2,  S.cerevisiae
KAR2
NP_012500.3
682 aa
KLLA0D09559g,  K.lactis
KLLA0D09559g
XP_453488.1
583 aa
AGOS_ACR038W,  E.gossypii
AGOS_ACR038W
NP_983441.1
674 aa
bip1,  S.pombe
bip1
NP_593245.1
663 aa
MGG_02503,  M.oryzae
MGG_02503
XP_003709308.1
664 aa
NCU03982,  N.crassa
NCU03982
XP_956567.1
661 aa
BIP2,  A.thaliana
BIP2
NP_851119.1
668 aa
BIP1,  A.thaliana
BIP1
NP_198206.1
669 aa
Os02g0115900,  O.sativa
Os02g0115900
NP_001045675.1
665 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Cell-surface GRP78 facilitates colorectal cancer cell migration and invasion.
Li Z, et al. Int J Biochem Cell Biol 45, 987-94 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HSP70 (pfam00012)
  Hsp70 protein.
PTZ00009 (PTZ00009)
  heat shock 70 kDa protein; Provisional.
HSP70 (pfam00012)
  Hsp70 protein.
NBD_sugar-kinase_HSP70_actin (cl17037)
  Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Hspa5 includes H.sapiens HSPA5 and R.norvegicus Hspa5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (69 transcripts, 35 species)
Liliopsida - monocots (24 transcripts, 9 species)
Coniferopsida - conifers (9 transcripts, 3 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)
Bryopsida - mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (3 transcripts, 2 species)

Chordata
Mammalia - mammals (23 transcripts, 15 species)
Actinopterygii - bony fishes (15 transcripts, 10 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (17 transcripts, 13 species)
Arachnida - arachnids (4 transcripts, 2 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (7 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (2 transcripts, 1 species)

Annelida
Polychaeta - segmented worms (2 transcripts, 1 species)
Hirudinida - segmented worms (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (22 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (4 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (2 transcripts, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (3 transcripts, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (2 transcripts, 1 species)

 

 

 

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