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Links from Protein

HomoloGene:77423. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

CATSPER2,  H.sapiens
cation channel, sperm associated 2
530 aa
CATSPER2,  P.troglodytes
cation channel, sperm associated 2
528 aa
LOC100609123,  P.troglodytes
cation channel sperm-associated protein 2-like
528 aa
CATSPER2,  M.mulatta
cation channel, sperm associated 2
528 aa
CATSPER2,  C.lupus
cation channel, sperm associated 2
527 aa
CATSPER2,  B.taurus
cation channel, sperm associated 2
529 aa
Catsper2,  M.musculus
cation channel, sperm associated 2
588 aa
Catsper2,  R.norvegicus
cation channel, sperm associated 2
584 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Regulation of fertilization in male rats by CatSper2 knockdown.
Zhang Z, et al. Asian J Androl 14, 301-9 (2012).
Hyperactivated sperm motility driven by CatSper2 is required for fertilization.
Quill TA, et al. Proc Natl Acad Sci U S A 100, 14869-74 (2003).
Identical phenotypes of CatSper1 and CatSper2 null sperm.
Carlson AE, et al. J Biol Chem 280, 32238-44 (2005).
Ion channels. Swimming with sperm.
Garbers DL. Nature 413, 579, 581-2 (2001).
CATSPER-Related Male Infertility
Hildebrand MS, et al. (1993).
A voltage-gated ion channel expressed specifically in spermatozoa.
Quill TA, et al. Proc Natl Acad Sci U S A 98, 12527-31 (2001).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ion_trans (pfam00520)
  Ion transport protein.
Ion_trans (pfam00520)
  Ion transport protein.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Catsper2 includes H.sapiens CATSPER2 and R.norvegicus Catsper2.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (9 transcripts, 9 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)




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