Display Settings:

Format

Send to:

Choose Destination

Links from Protein

HomoloGene:3690. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PLK1,  H.sapiens
polo-like kinase 1
NP_005021.2
603 aa
PLK1,  P.troglodytes
polo-like kinase 1
XP_001163623.2
746 aa
PLK1,  M.mulatta
polo-like kinase 1
XP_001092070.1
603 aa
PLK1,  C.lupus
polo-like kinase 1
XP_547091.3
604 aa
PLK1,  B.taurus
polo-like kinase 1
NP_001033262.1
602 aa
Plk1,  M.musculus
polo-like kinase 1
NP_035251.3
603 aa
Plk1,  R.norvegicus
polo-like kinase 1
NP_058796.1
603 aa
PLK1,  G.gallus
polo-like kinase 1
NP_001025810.1
595 aa
plk1,  X.tropicalis
polo-like kinase 1
NP_998844.1
598 aa
plk1,  D.rerio
polo-like kinase 1 (Drosophila)
NP_001003890.3
595 aa
polo,  D.melanogaster
polo
NP_001014592.1
576 aa
AgaP_AGAP004239,  A.gambiae
AgaP_AGAP004239
XP_313155.3
575 aa
plk-1,  C.elegans
plk-1
NP_001021173.1
648 aa
plk-2,  C.elegans
plk-2
NP_491036.1
632 aa
CDC5,  S.cerevisiae
CDC5
NP_013714.1
705 aa
KLLA0C06138g,  K.lactis
KLLA0C06138g
XP_452471.1
708 aa
AGOS_ACL006W,  E.gossypii
AGOS_ACL006W
NP_983398.2
709 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Polo kinase Cdc5 is a central regulator of meiosis I.
Attner MA, et al. Proc Natl Acad Sci U S A 110, 14278-83 (2013).
[Effect of Plk1 330/597 serine phosphorylated mutant on cytokinesis during mitosis].
Cheng L, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 28, 1016-9 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
S_TKc (smart00220)
  Serine/Threonine protein kinases, catalytic domain.
POLO_box (cl02916)
  Polo-box domain (PBD), a C-terminal tandemly repeated region of polo-like kinases.
Pkinase (pfam00069)
  Protein kinase domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Plk1 includes H.sapiens PLK1 and R.norvegicus Plk1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 11 species)
Actinopterygii - bony fishes (10 transcripts, 9 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (13 transcripts, 8 species)
Branchiopoda - crustaceans (5 transcripts, 1 species)
Arachnida - arachnids (2 transcripts, 2 species)
Maxillopoda - crustaceans (2 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (6 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (4 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (3 transcripts, 1 species)
Polychaeta - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (3 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Ciliophora
Oligohymenophorea - ciliates (6 transcripts, 2 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

Support Center