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HomoloGene:18258. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ANKK1,  H.sapiens
ankyrin repeat and kinase domain containing 1
NP_848605.1
765 aa
ANKK1,  P.troglodytes
ankyrin repeat and kinase domain containing 1
XP_003952091.1
765 aa
ANKK1,  C.lupus
ankyrin repeat and kinase domain containing 1
XP_546521.2
764 aa
ANKK1,  B.taurus
ankyrin repeat and kinase domain containing 1
XP_003586985.1
1004 aa
Ankk1,  M.musculus
ankyrin repeat and kinase domain containing 1
NP_766510.1
745 aa
Ankk1,  R.norvegicus
ankyrin repeat and kinase domain containing 1
XP_006243085.1
773 aa
ANKK1,  G.gallus
ankyrin repeat and kinase domain containing 1
XP_003642663.2
830 aa
ankk1,  X.tropicalis
ankyrin repeat and kinase domain containing 1
XP_002937872.1
766 aa
ankk1,  D.rerio
ankyrin repeat and kinase domain containing 1
NP_001124137.1
733 aa
KEG,  A.thaliana
KEG
NP_196857.2
1625 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Dopamine receptor D2, reduced brain density of.



Publications
Articles associated with genes and sequences of this homology group.

[ANKK1 gene in psychiatry].
Suchanecka A, et al. Psychiatr Pol 45, 349-56 (2011).
Effect of the TaqIA polymorphism on ethanol response in the brain.
London ED, et al. Psychiatry Res 174, 163-70 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TyrKc (smart00219)
  Tyrosine kinase, catalytic domain.
Ank_2 (pfam12796)
  Ankyrin repeats (3 copies).
Ank_5 (pfam13857)
  Ankyrin repeats (many copies).
S_TKc (smart00220)
  Serine/Threonine protein kinases, catalytic domain.
Pkinase_Tyr (pfam07714)
  Protein tyrosine kinase.
Ank_4 (pfam13637)
  Ankyrin repeats (many copies).
Arp (COG0666)
  FOG: Ankyrin repeat [General function prediction only].
ANK (cd00204)
  ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
Ank_2 (pfam12796)
  Ankyrin repeats (3 copies).
Ank_4 (pfam13637)
  Ankyrin repeats (many copies).
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
RING (cl17238)
  RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ankk1 includes H.sapiens ANKK1 and R.norvegicus Ankk1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (18 transcripts, 14 species)
Liliopsida - monocots (8 transcripts, 7 species)

Chordata
Mammalia - mammals (3 transcripts, 3 species)
Actinopterygii - bony fishes (1 transcript, 1 species)

Ascomycota
Pezizomycetes - ascomycetes (3 transcripts, 1 species)
Sordariomycetes - ascomycetes (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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