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HomoloGene:7917. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RFX3,  H.sapiens
regulatory factor X, 3 (influences HLA class II expression)
NP_001269045.1
749 aa
RFX3,  P.troglodytes
regulatory factor X, 3 (influences HLA class II expression)
XP_520464.2
739 aa
RFX3,  M.mulatta
regulatory factor X, 3 (influences HLA class II expression)
XP_001086729.2
782 aa
RFX3,  C.lupus
regulatory factor X, 3 (influences HLA class II expression)
XP_005615977.1
754 aa
LOC538070,  B.taurus
transcription factor RFX3-like
XP_005210053.1
749 aa
Rfx3,  M.musculus
regulatory factor X, 3 (influences HLA class II expression)
NP_001159886.1
749 aa
RFX3,  G.gallus
regulatory factor X, 3 (influences HLA class II expression)
XP_004949116.1
749 aa
rfx3,  X.tropicalis
regulatory factor X, 3 (influences HLA class II expression)
NP_001263620.1
749 aa
rfx3,  D.rerio
regulatory factor X, 3 (influences HLA class II expression)
NP_001073517.1
765 aa
Rfx,  D.melanogaster
Rfx
NP_001247022.2
860 aa
AgaP_AGAP003943,  A.gambiae
AgaP_AGAP003943
XP_318401.5
730 aa
daf-19,  C.elegans
daf-19
NP_001254236.1
661 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Ciliogenic RFX transcription factors regulate FGF1 gene promoter.
Hsu YC, et al. J Cell Biochem 113, 2511-22 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RFX_DNA_binding (pfam02257)
  RFX DNA-binding domain.
RFX1_trans_act (pfam04589)
  RFX1 transcription activation region.
PRTP (pfam01366)
  Herpesvirus processing and transport protein.
RFX_DNA_binding (pfam02257)
  RFX DNA-binding domain.
RFX1_trans_act (pfam04589)
  RFX1 transcription activation region.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rfx3 includes H.sapiens RFX3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (16 transcripts, 10 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

 

 

 

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