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HomoloGene:134616. Gene conserved in Diptera Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

Jon25Bi,  D.melanogaster
Jonah 25Bi
NP_001033873.1
266 aa
Jon66Ci,  D.melanogaster
Jonah 66Ci
NP_729372.1
260 aa
Jon66Cii,  D.melanogaster
Jonah 66Cii
NP_648217.1
262 aa
Jon25Biii,  D.melanogaster
Jonah 25Biii
NP_608881.1
258 aa
Jon99Ciii,  D.melanogaster
Jonah 99Ciii
NP_733330.1
265 aa
Jon99Cii,  D.melanogaster
Jonah 99Cii
NP_524554.1
265 aa
Jon99Fii,  D.melanogaster
Jonah 99Fii
NP_651799.1
267 aa
Jon99Ci,  D.melanogaster
Jonah 99Ci
NP_524555.1
272 aa
Jon99Fi,  D.melanogaster
Jonah 99Fi
NP_651800.2
267 aa
Jon44E,  D.melanogaster
Jonah 44E
NP_724699.1
271 aa
CG18180,  D.melanogaster
CG18180
NP_648341.1
264 aa
sphinx1,  D.melanogaster
sphinx1
NP_729255.2
253 aa
sphinx2,  D.melanogaster
sphinx2
NP_729256.2
253 aa
CG18179,  D.melanogaster
CG18179
NP_648340.1
268 aa
CG8329,  D.melanogaster
CG8329
NP_648339.1
259 aa
Jon25Bii,  D.melanogaster
Jonah 25Bii
NP_608882.1
276 aa
CG3088,  D.melanogaster
CG3088
NP_648334.1
252 aa
Jon65Ai,  D.melanogaster
Jonah 65Ai
NP_648015.1
262 aa
yip7,  D.melanogaster
yippee interacting protein 7
NP_523944.1
270 aa
CG7542,  D.melanogaster
CG7542
NP_648995.3
270 aa
CG10472,  D.melanogaster
CG10472
NP_648017.1
290 aa
Jon65Aiv,  D.melanogaster
Jonah 65Aiv
NP_648012.1
271 aa
Jon74E,  D.melanogaster
Jonah 74E
NP_648994.1
412 aa
CG6592,  D.melanogaster
CG6592
NP_648016.1
438 aa
CG10477,  D.melanogaster
CG10477
NP_648010.1
272 aa
Jon65Aiii,  D.melanogaster
Jonah 65Aiii
NP_648013.1
274 aa
Jon65Aii,  D.melanogaster
Jonah 65Aii
NP_648014.1
259 aa
AgaP_AGAP012736,  A.gambiae
AgaP_AGAP012736
XP_307014.4
340 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

D.melanogaster
Expressed abundantly in larval gut. Mutants dncM11 and dncM14 show lower levels of Ser99Da RNA than normal flies; levels of cAMP, however, are elevated in the mutants. The Ser99Da-related genes Ser99Db and Ser99Dc (with same location and cytology) are not expressed differentially in dnc mutants.
The Jon genes are expressed in various regions of the larval midgut (AMG, MMG, PMG) during all the larval stages (Akam and Carlson, 1985); expression disappears at pupation, but reappears in the adult midgut shortly after eclosion and remains throughout adult life.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tryp_SPc (smart00020)
  Trypsin-like serine protease.
Tryp_SPc (cd00190)
  Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

 

 

 

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