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HomoloGene:74542. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CACNA1F,  H.sapiens
calcium channel, voltage-dependent, L type, alpha 1F subunit
NP_005174.2
1977 aa
CACNA1F,  M.mulatta
calcium channel, voltage-dependent, L type, alpha 1F subunit
XP_001106163.2
1911 aa
CACNA1F,  C.lupus
calcium channel, voltage-dependent, L type, alpha 1F subunit
XP_005642146.1
1971 aa
CACNA1F,  B.taurus
calcium channel, voltage-dependent, L type, alpha 1F subunit
NP_001192592.1
1972 aa
Cacna1f,  M.musculus
calcium channel, voltage-dependent, alpha 1F subunit
NP_062528.2
1984 aa
Cacna1f,  R.norvegicus
calcium channel, voltage-dependent, L type, alpha 1F subunit
NP_446153.1
1981 aa
cacna1f,  X.tropicalis
calcium channel, voltage-dependent, L type, alpha 1F subunit
XP_002941018.2
1982 aa
LOC559964,  D.rerio
novel protein similar to vertebrate voltage-dependent calcium channel P/Q type alpha 1 subunit (CACNA1)
XP_003199134.2
2065 aa
LOC793708,  D.rerio
calcium channel, voltage-dependent, L type, alpha 1F subunit-like
XP_001333514.5
2118 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Night blindness, congenital stationary, X-linked, type 2.
Cone-rod dystrophy, X-linked, 3.



Publications
Articles associated with genes and sequences of this homology group.

Calcium channel-dependent molecular maturation of photoreceptor synapses.
Zabouri N & Haverkamp S. PLoS One 8, e63853 (2013).
Visual signal pathway reorganization in the Cacna1f mutant rat model.
Tao Y, et al. Invest Ophthalmol Vis Sci 54, 1988-97 (2013).
What can naturally occurring mutations tell us about Ca(v)1.x channel function?
Stockner T & Koschak A. Biochim Biophys Acta 1828, 1598-607 (2013).
Outer retinal structural anomaly due to frameshift mutation in CACNA1F gene.
Vincent A & Héon E. Eye (Lond) 26, 1278-80 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ca_chan_IQ (cl07394)
  Voltage gated calcium channel IQ domain.
Ion_trans (pfam00520)
  Ion transport protein.
Ion_trans (pfam00520)
  Ion transport protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cacna1f includes H.sapiens CACNA1F and R.norvegicus Cacna1f.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 5 species)
Actinopterygii - bony fishes (3 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

 

 

 

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