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HomoloGene:8383. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RAX,  H.sapiens
retina and anterior neural fold homeobox
NP_038463.2
346 aa
RAX,  P.troglodytes
retina and anterior neural fold homeobox
XP_001142510.1
346 aa
RAX,  M.mulatta
retina and anterior neural fold homeobox
XP_001087324.1
347 aa
RAX,  C.lupus
retina and anterior neural fold homeobox
XP_852642.2
288 aa
RAX,  B.taurus
retina and anterior neural fold homeobox
XP_003587831.1
352 aa
Rax,  M.musculus
retina and anterior neural fold homeobox
NP_038861.2
342 aa
Rax,  R.norvegicus
retina and anterior neural fold homeobox
NP_446130.1
342 aa
RAX,  G.gallus
retina and anterior neural fold homeobox
NP_001230653.1
317 aa
rax,  X.tropicalis
retina and anterior neural fold homeobox
XP_002936715.1
326 aa
rx3,  D.rerio
retinal homeobox gene 3
NP_571302.1
292 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Microphthalmia, isolated 3.



Publications
Articles associated with genes and sequences of this homology group.

RAX and anophthalmia in humans: evidence of brain anomalies.
Abouzeid H, et al. Mol Vis 18, 1449-56 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
OAR (pfam03826)
  OAR domain.
OAR (pfam03826)
  OAR domain.
homeodomain (cl00084)
  Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rax includes H.sapiens RAX and R.norvegicus Rax.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (5 transcripts, 3 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

 

 

 

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