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HomoloGene:3133. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

EFTUD2,  H.sapiens
elongation factor Tu GTP binding domain containing 2
NP_001245282.1
972 aa
EFTUD2,  P.troglodytes
elongation factor Tu GTP binding domain containing 2
XP_001145980.1
972 aa
EFTUD2,  M.mulatta
elongation factor Tu GTP binding domain containing 2
XP_001114964.1
937 aa
EFTUD2,  C.lupus
elongation factor Tu GTP binding domain containing 2
XP_005624439.1
972 aa
EFTUD2,  B.taurus
elongation factor Tu GTP binding domain containing 2
NP_001076865.1
972 aa
Eftud2,  M.musculus
elongation factor Tu GTP binding domain containing 2
NP_001103465.1
972 aa
Eftud2,  R.norvegicus
elongation factor Tu GTP binding domain containing 2
XP_213492.3
972 aa
EFTUD2,  G.gallus
elongation factor Tu GTP binding domain containing 2
NP_001026672.1
972 aa
eftud2,  X.tropicalis
elongation factor Tu GTP binding domain containing 2
NP_001025537.1
974 aa
eftud2,  D.rerio
elongation factor Tu GTP binding domain containing 2
NP_956802.2
973 aa
CG4849,  D.melanogaster
CG4849
NP_651605.1
975 aa
eftu-2,  C.elegans
eftu-2
NP_498308.1
974 aa
SNU114,  S.cerevisiae
SNU114
NP_012748.1
1008 aa
KLLA0A06688g,  K.lactis
KLLA0A06688g
XP_451298.1
933 aa
AGOS_AEL124W,  E.gossypii
AGOS_AEL124W
NP_984737.1
940 aa
cwf10,  S.pombe
cwf10
NP_596689.2
984 aa
MGG_13500,  M.oryzae
MGG_13500
XP_003716278.1
989 aa
NCU02572,  N.crassa
NCU02572
XP_965703.2
989 aa
MEE5,  A.thaliana
MEE5
NP_172112.1
987 aa
AT5G25230,  A.thaliana
AT5G25230
NP_197905.1
973 aa
Os06g0608300,  O.sativa
Os06g0608300
NP_001058038.1
997 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
???.



Publications
Articles associated with genes and sequences of this homology group.

EFTUD2 haploinsufficiency leads to syndromic oesophageal atresia.
Gordon CT, et al. J Med Genet 49, 737-46 (2012).
Architecture of the spliceosome.
van der Feltz C, et al. Biochemistry 51, 3321-33 (2012).
VAJ/GFA1/CLO is involved in the directional control of floral organ growth.
Yagi N, et al. Plant Cell Physiol 50, 515-27 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
EFG_like_IV (cl02789)
  Elongation Factor G-like domain IV. This family includes the translational elongation factor termed EF-2 (for Archaea and Eukarya) and EF-G (for Bacteria), ribosomal protection proteins that mediate tetracycline resistance and, an evolutionarily ...
EFG_II (pfam14492)
  Elongation Factor G, domain II.
Elongation_Factor_C (cl02785)
  Elongation factor G C-terminus. This domain includes the carboxyl terminal regions of elongation factors (EFs) bacterial EF-G, eukaryotic and archeal EF-2 and eukaryotic mitochondrial mtEFG1s and mtEFG2s. This group also includes proteins similar to the ...
Translation_Factor_II_like (cl02787)
  Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to ...
Ras_like_GTPase (cl17170)
  Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Eftud2 includes H.sapiens EFTUD2 and R.norvegicus Eftud2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (16 transcripts, 15 species)
Actinopterygii - bony fishes (15 transcripts, 10 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Amniota - vertebrates (3 transcripts, 1 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 8 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (4 transcripts, 2 species)

Porifera
Demospongiae - sponges (3 transcripts, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (39 transcripts, 28 species)
Liliopsida - monocots (14 transcripts, 9 species)
Coniferopsida - conifers (4 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (2 transcripts, 2 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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