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HomoloGene:121495. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

NR3C2,  H.sapiens
nuclear receptor subfamily 3, group C, member 2
NP_000892.2
984 aa
NR3C2,  P.troglodytes
nuclear receptor subfamily 3, group C, member 2
XP_001150516.1
984 aa
NR3C2,  M.mulatta
nuclear receptor subfamily 3, group C, member 2
XP_001099855.2
1040 aa
NR3C2,  C.lupus
nuclear receptor subfamily 3, group C, member 2
XP_003639585.2
1020 aa
NR3C2,  B.taurus
nuclear receptor subfamily 3, group C, member 2
NP_001178278.1
984 aa
Nr3c2,  M.musculus
nuclear receptor subfamily 3, group C, member 2
NP_001077375.1
980 aa
Nr3c2,  R.norvegicus
nuclear receptor subfamily 3, group C, member 2
NP_037263.1
981 aa
NR3C2,  G.gallus
nuclear receptor subfamily 3, group C, member 2
NP_001152817.1
981 aa
nr3c2,  X.tropicalis
nuclear receptor subfamily 3, group C, member 2
XP_002933547.2
981 aa
nr3c2,  D.rerio
nuclear receptor subfamily 3, group C, member 2
NP_001093873.1
970 aa
LOC100534796,  D.rerio
mineralocorticoid receptor-like
XP_003197725.1
588 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Pseudohypoaldosteronism type I, autosomal dominant.
Hypertension, early-onset, autosomal dominant, with exacerbation in pregnancy.



Publications
Articles associated with genes and sequences of this homology group.

The ubiquitous mineralocorticoid receptor: clinical implications.
Hawkins UA, et al. Curr Hypertens Rep 14, 573-80 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PHA03255 (PHA03255)
  BDLF3; Provisional.
Levi_coat (pfam01819)
  Levivirus coat protein.
Herpes_TAF50 (pfam03326)
  Herpesvirus transcription activation factor (transactivator).
DUF566 (pfam04484)
  Family of unknown function (DUF566).
Speriolin_N (pfam15058)
  Speriolin N terminus.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nr3c2 includes H.sapiens NR3C2 and R.norvegicus Nr3c2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 10 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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